H
Hannah M. Bacon
Researcher at University of Virginia
Publications - 2
Citations - 63
Hannah M. Bacon is an academic researcher from University of Virginia. The author has contributed to research in topics: Endothelial stem cell & Purinergic signalling. The author has an hindex of 2, co-authored 2 publications receiving 32 citations.
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Journal ArticleDOI
Endothelial cell Pannexin1 modulates severity of ischemic stroke by regulating cerebral inflammation and myogenic tone.
Miranda E. Good,Stephanie A. Eucker,Jun Li,Hannah M. Bacon,Susan M. Lang,Joshua T. Butcher,Tyler Johnson,Ronald P.A. Gaykema,Manoj K. Patel,Zhiyi Zuo,Brant E. Isakson +10 more
TL;DR: Examination of the role of smooth muscle and endothelial cell Panx1 in cerebral ischemia/reperfusion injury outcomes concluded that deletion of endothelial PanX1 mitigated cerebral ischemic injury by reducing inflammation and myogenic tone development, indicating that endothelialPanx1 is a possible novel target for therapeutic intervention of isChemic stroke.
Journal ArticleDOI
A venous-specific purinergic signaling cascade initiated by Pannexin 1 regulates TNFα-induced increases in endothelial permeability
Daniela Maier-Begandt,Daniela Maier-Begandt,Heather Skye Comstra,Samuel A. Molina,Nenja Krüger,Nenja Krüger,Claire A. Ruddiman,Yen Lin Chen,Xiaobin Chen,Lauren A Biwer,Scott R. Johnstone,Alexander W. Lohman,Miranda E. Good,Leon J. DeLalio,Kwangseok Hong,Hannah M. Bacon,Zhen Yan,Swapnil K. Sonkusare,Michael Koval,Brant E. Isakson +19 more
TL;DR: In this article, the effects of the proinflammatory cytokine TNFα on transendothelial permeability and electrophysiology in ex vivo murine veins and arteries were studied.