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Zhen Yan

Researcher at Chinese Academy of Sciences

Publications -  180
Citations -  19318

Zhen Yan is an academic researcher from Chinese Academy of Sciences. The author has contributed to research in topics: Skeletal muscle & Mitochondrial biogenesis. The author has an hindex of 57, co-authored 162 publications receiving 16257 citations. Previous affiliations of Zhen Yan include National Institutes of Health & Kunming Institute of Zoology.

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Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition)

Daniel J. Klionsky, +2522 more
- 21 Jan 2016 - 
TL;DR: In this paper, the authors present a set of guidelines for the selection and interpretation of methods for use by investigators who aim to examine macro-autophagy and related processes, as well as for reviewers who need to provide realistic and reasonable critiques of papers that are focused on these processes.
Journal ArticleDOI

Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition)

Daniel J. Klionsky, +2983 more
- 08 Feb 2021 - 
TL;DR: In this article, the authors present a set of guidelines for investigators to select and interpret methods to examine autophagy and related processes, and for reviewers to provide realistic and reasonable critiques of reports that are focused on these processes.
Journal ArticleDOI

Exercise Stimulates Pgc-1α Transcription in Skeletal Muscle through Activation of the p38 MAPK Pathway

TL;DR: It is reported that a single bout of voluntary running induced a transient increase of Pgc-1α mRNA expression in mouse plantaris muscle, concurrent with an activation of the p38 MAPK pathway, suggesting that contractile activity-induced activation ofThe p38MAPK pathway promotes PGC-1 α gene expression and skeletal muscle adaptation.
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Skeletal Muscle Fiber-type Switching, Exercise Intolerance, and Myopathy in PGC-1α Muscle-specific Knock-out Animals

TL;DR: A critical role is demonstrated for PGC-1α in maintenance of normal fiber type composition and of muscle fiber integrity following exertion in skeletal muscle knock-out animals.