H
Hans-Ulrich Bernard
Researcher at University of California, Irvine
Publications - 38
Citations - 6846
Hans-Ulrich Bernard is an academic researcher from University of California, Irvine. The author has contributed to research in topics: DNA methylation & Methylation. The author has an hindex of 27, co-authored 38 publications receiving 6419 citations. Previous affiliations of Hans-Ulrich Bernard include Institute of Molecular and Cell Biology & International Agency for Research on Cancer.
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Journal ArticleDOI
Classification of papillomaviruses
Ethel Michele De Villiers,Claude M. Fauquet,Thomas R. Broker,Hans-Ulrich Bernard,Harald zur Hausen +4 more
TL;DR: The higher-order PV taxonomy is described following the general criteria established by the International Committee on the Taxonomy of Viruses (ICTV), reviews the literature of the lower order taxa, lists all known "PV types", and interprets their phylogenetic relationship.
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Classification of Papillomaviruses (PVs) Based on 189 PV Types and Proposal of Taxonomic Amendments
Hans-Ulrich Bernard,Robert D. Burk,Zigui Chen,Koenraad Van Doorslaer,Harald zur Hausen,Ethel Michele De Villiers +5 more
TL;DR: It is discussed that based on emerging species concepts derived from genome sequences, PV types could be promoted to the taxonomic level of species, but it is not recommended to implement this change at the current time.
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The clinical importance of the nomenclature, evolution and taxonomy of human papillomaviruses.
TL;DR: Human papillomaviruses evolved together with humankind and Homo sapiens was never without HPVs, and consequently never without warts and cervical cancer.
Journal ArticleDOI
Genome variation of human papillomavirus types: Phylogenetic and medical implications
TL;DR: The study of HPV type variation may point to one of the reasons for the higher incidence rates of these lesions in specific cohorts, as well as suggest that variants of the same HPV type are biologically distinct and may confer differential pathogenic risks.
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CpG Methylation of Human Papillomavirus Type 16 DNA in Cervical Cancer Cell Lines and in Clinical Specimens: Genomic Hypomethylation Correlates with Carcinogenic Progression
Vinay Badal,Linda S. H. Chuang,Eileen Hwee-Hong Tan,Sushma Badal,Luisa L. Villa,Cosette M. Wheeler,Benjamin F. L. Li,Hans-Ulrich Bernard +7 more
TL;DR: It is reported that HPV genomes are efficiently targeted in vivo by CpG methylation, a well-known mechanism of transcriptional repression, and opens research on the importance of this mechanism during the viral life cycle, and provides a marker relevant for the etiology and diagnosis of cervical cancer.