H
Hao-Rui Si
Researcher at Chinese Academy of Sciences
Publications - 9
Citations - 277
Hao-Rui Si is an academic researcher from Chinese Academy of Sciences. The author has contributed to research in topics: Medicine & Biology. The author has an hindex of 3, co-authored 5 publications receiving 169 citations.
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Journal ArticleDOI
Infection with novel coronavirus (SARS-CoV-2) causes pneumonia in Rhesus macaques.
Chao Shan,Yanfeng Yao,Xing-Lou Yang,Yiwu Zhou,Ge Gao,Yun Peng,Lian Yang,Xue Hu,Jin Xiong,Ren-Di Jiang,Huajun Zhang,Xiaoxiao Gao,Cheng Peng,Juan Min,Ying Chen,Hao-Rui Si,Jia Wu,Peng Zhou,Yan-Yi Wang,Hongping Wei,Wei Pang,Zheng-Fei Hu,Longbao Lv,Yong-Tang Zheng,Zhengli Shi,Zhiming Yuan +25 more
TL;DR: It is demonstrated that neutralizing antibodies generated from the primary infection could protect the Rhesus macaques from a second-round challenge by SARS-CoV-2, and the non-human primate model that is established here provides a valuable platform to study Sars-Co V-2 pathogenesis and to evaluate candidate vaccines and therapeutics.
Journal ArticleDOI
Identification of a novel lineage bat SARS-related coronaviruses that use bat ACE2 receptor.
Hua Guo,Ben Hu,Hao-Rui Si,Yan Zhu,Wei Zhang,Bei Li,Ang Li,Rong Geng,Hao-Feng Lin,Xing-Lou Yang,Peng Zhou,Zhengli Shi +11 more
TL;DR: One of the unsolved scientific questions of SARS-CoV-2 is the animal origin of t... as mentioned in this paper, which has been the most devastating disease COVID-19 in the century.
Journal ArticleDOI
A bat MERS-like coronavirus circulates in pangolins and utilizes human DPP4 and host proteases for cell entry
Jing Chen,Xing-Lou Yang,Hao-Rui Si,Qian-chun Gong,Teng Cheng Que,Jing Li,Yang Li,Chunguang Wu,Wei Zhang,Ying Chen,Yun Luo,Yan Zhu,Bei Li,Dong-Sheng Luo,Ben Hu,Haofeng Lin,Ren-Di Jiang,Ting-Ting Jiang,Qian Li,Meiqin Liu,Shizhe Xie,Jia Su,Xiaoshuang Zheng,Ang Li,Y. Yao,Yong-Sung Yang,Panyu Chen,Aiqiong Wu,Meihong He,Xinhua Lin,Yigang Tong,Yan-Ling Hu,Zhengli Shi,P. Zhou +33 more
TL;DR: A novel MERS-like coronavirus in Malayan pangolins, named Manis javanica HKU4-related CoV (MjHKU4r-CoV), was reported in this article .
Journal ArticleDOI
Correction for Li et al., "Discovery of Bat Coronaviruses through Surveillance and Probe Capture-Based Next-Generation Sequencing".
Bei Li,Hao-Rui Si,Yan Zhu,Xing-Lou Yang,Danielle E. Anderson,Zhengli Shi,Lin-Fa Wang,Peng Zhou +7 more
TL;DR: The following sentence should be added to the “Data availability” paragraph: “Raw next-generation sequencing data have been deposited in the NCBI SRA database under accession no.SRR11085733”.
Posted ContentDOI
Identification of a novel lineage bat SARS-related coronaviruses that use bat ACE2 receptor
Hua Guo,Ben Hu,Hao-Rui Si,Yan Zhu,Wei Zhang,Bei Li,Ang Li,Rong Geng,Hao-Feng Lin,Xing-Lou Yang,Peng Zhou,Zhengli Shi +11 more
TL;DR: In this paper, the authors reported the identification of a novel lineage of SARS-CoV-2 related viruses, including RaTG15 and seven other viruses, from bats at the same location where they found RaTG13 in 2015.