H
Harald Binder
Researcher at University of Freiburg
Publications - 343
Citations - 10723
Harald Binder is an academic researcher from University of Freiburg. The author has contributed to research in topics: Medicine & Population. The author has an hindex of 45, co-authored 302 publications receiving 7692 citations. Previous affiliations of Harald Binder include University Medical Center Freiburg & University of Mainz.
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Selection of important variables and determination of functional form for continuous predictors in multivariable model building.
TL;DR: It is argued why MFP is the preferred approach for multivariable model building with continuous covariates, and it is shown that spline modelling, while extremely flexible, can generate fitted curves with uninterpretable 'wiggles'.
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Genetic Cell Ablation Reveals Clusters of Local Self-Renewing Microglia in the Mammalian Central Nervous System.
Julia Bruttger,Khalad Karram,Simone Wörtge,Tommy Regen,Federico Marini,Nicola Hoppmann,Matthias Klein,Thomas Blank,Simon Yona,Yochai Wolf,Matthias Mack,Emmanuel Pinteaux,Werner Müller,Frauke Zipp,Harald Binder,Tobias Bopp,Marco Prinz,Steffen Jung,Ari Waisman +18 more
TL;DR: It was found that the microglial compartment was reconstituted within 1 week of depletion, and microglia have the potential for efficient self-renewal without the contribution of peripheral myeloid cells, and IL-1R signaling participates in this restorative proliferation process.
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A graphical tool for locating inconsistency in network meta-analyses
TL;DR: The net heat plot is provided, to render transparent which direct comparisons drive each network estimate and to display hot spots of inconsistency, which permits singling out which of the suspicious direct comparisons are sufficient to explain the presence of inconsistency.
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Bioresorbable Coronary Scaffold Thrombosis: Multicenter Comprehensive Analysis of Clinical Presentation, Mechanisms, and Predictors.
Serban Puricel,Florim Cuculi,Melissa Weissner,Axel Schmermund,Peiman Jamshidi,Tobias Nyffenegger,Harald Binder,Holger Eggebrecht,Thomas Münzel,Stéphane Cook,Tommaso Gori +10 more
TL;DR: The 12-month incidence of ScT reached 3% and could be significantly reduced when an optimized implantation strategy was employed, an effect that remained significant when adjusted for multivariable propensity score.
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Effect of nighttime aircraft noise exposure on endothelial function and stress hormone release in healthy adults
Frank P. Schmidt,Mathias Basner,Gunnar Kröger,Stefanie Weck,Boris Schnorbus,Axel Muttray,Murat Sariyar,Harald Binder,Tommaso Gori,Ascan Warnholtz,Thomas Münzel +10 more
TL;DR: In healthy adults, acute nighttime aircraft noise exposure dose-dependently impairs endothelial function and stimulates adrenaline release and may be one mechanism contributing to the observed association of chronic noise exposure with cardiovascular disease.