F
Federico Marini
Researcher at University of Mainz
Publications - 71
Citations - 1951
Federico Marini is an academic researcher from University of Mainz. The author has contributed to research in topics: Medicine & Biology. The author has an hindex of 16, co-authored 47 publications receiving 1079 citations.
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Journal ArticleDOI
Genetic Cell Ablation Reveals Clusters of Local Self-Renewing Microglia in the Mammalian Central Nervous System.
Julia Bruttger,Khalad Karram,Simone Wörtge,Tommy Regen,Federico Marini,Nicola Hoppmann,Matthias Klein,Thomas Blank,Simon Yona,Yochai Wolf,Matthias Mack,Emmanuel Pinteaux,Werner Müller,Frauke Zipp,Harald Binder,Tobias Bopp,Marco Prinz,Steffen Jung,Ari Waisman +18 more
TL;DR: It was found that the microglial compartment was reconstituted within 1 week of depletion, and microglia have the potential for efficient self-renewal without the contribution of peripheral myeloid cells, and IL-1R signaling participates in this restorative proliferation process.
Journal ArticleDOI
Orchestrating Single-Cell Analysis with Bioconductor
Robert A. Amezquita,Aaron T. L. Lun,Aaron T. L. Lun,Etienne Becht,Vincent J. Carey,Lindsay N. Carpp,Ludwig Geistlinger,Federico Marini,Kevin Rue-Albrecht,Davide Risso,Davide Risso,Charlotte Soneson,Charlotte Soneson,Levi Waldron,Hervé Pagès,Mike L. Smith,Wolfgang Huber,Martin Morgan,Raphael Gottardo,Stephanie C. Hicks +19 more
TL;DR: This Perspective highlights open-source software for single-cell analysis released as part of the Bioconductor project, providing an overview for users and developers.
Journal ArticleDOI
pcaExplorer: an R/Bioconductor package for interacting with RNA-seq principal components.
Federico Marini,Harald Binder +1 more
TL;DR: The pcaExplorer software package is developed to enhance commonly performed analysis steps with an interactive and user-friendly application, which provides state saving as well as the automated creation of reproducible reports.
Posted ContentDOI
pcaExplorer: an R/Bioconductor package for interacting with RNA-seq principal components
Federico Marini,Harald Binder +1 more
TL;DR: The pcaExplorer software package is developed to enhance commonly performed analysis steps with an interactive and user-friendly application, which provides state saving as well as the automated creation of reproducible reports.
Journal ArticleDOI
Integrated longitudinal immunophenotypic, transcriptional and repertoire analyses delineate immune responses in COVID-19 patients.
Samuele Notarbartolo,Valeria Ranzani,Alessandra Bandera,Alessandra Bandera,Paola Gruarin,Valeria Bevilacqua,Anna Rita Putignano,Andrea Gobbini,Andrea Gobbini,Eugenia Galeota,Cristina Manara,Mauro Bombaci,Elisa Pesce,Elena Zagato,Andrea Favalli,Maria Lucia Sarnicola,Serena Curti,Mariacristina Crosti,Martina Martinovic,Tanya Fabbris,Federico Marini,Lorena Donnici,Mariangela Lorenzo,Marilena Mancino,Riccardo Ungaro,Andrea Lombardi,Davide Mangioni,Antonio Muscatello,Stefano Aliberti,Stefano Aliberti,Francesco Blasi,Tullia Maria De Feo,Daniele Prati,Lara Manganaro,Francesca Granucci,Francesca Granucci,Antonio Lanzavecchia,Raffaele De Francesco,Andrea Gori,Andrea Gori,Renata Grifantini,Sergio Abrignani +41 more
TL;DR: In this article, the authors integrated phenotypic, transcriptional and repertoire analyses on PBMCs from mild and severe COVID-19 patients during and after infection, and compared them to healthy donors (HD).