H
Harald Hoffmann
Researcher at Synlab Group
Publications - 59
Citations - 2870
Harald Hoffmann is an academic researcher from Synlab Group. The author has contributed to research in topics: Tuberculosis & Mycobacterium tuberculosis. The author has an hindex of 24, co-authored 53 publications receiving 2371 citations. Previous affiliations of Harald Hoffmann include World Health Organization.
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The geographic diversity of nontuberculous mycobacteria isolated from pulmonary samples: an NTM-NET collaborative study
Wouter Hoefsloot,Jakko van Ingen,Claire Andrejak,Kristian Ängeby,Rosine Bauriaud,Pascale Bémer,Natalie Beylis,Martin J. Boeree,Juana Cacho,Violet N. Chihota,Erica Chimara,Gavin J. Churchyard,Raquel Cias,Rosa Daza,Charles L. Daley,P. N. Richard Dekhuijzen,Diego Domingo,Francis Drobniewski,Jaime Esteban,Maryse Fauville-Dufaux,Dorte Bek Folkvardsen,Noel Gibbons,Enrique Gómez-Mampaso,Rosa Gonzalez,Harald Hoffmann,Po-Ren Hsueh,Alexander Indra,Tomasz Jagielski,Frances Jamieson,Mateja Janković,Eefje Jong,Joseph Keane,Wo Jung Koh,Berit Lange,Sylvia Cardoso Leão,Rita Macedo,Turid Mannsåker,Theodore K. Marras,Jeannette Maugein,Heather Milburn,Tamas Mlinkó,Nora Morcillo,Kozo Morimoto,Dimitrios Papaventsis,Elia Palenque,Mar Paez-Peña,Claudio Piersimoni,Monika Polanova,Nalin Rastogi,Elvira Richter,Maria Jesus Ruiz-Serrano,Anabela Santos Silva,M. Pedro Da Silva,M. Pedro Da Silva,Hülya Şimşek,Dick van Soolingen,Nora Szabó,Rachel Thomson,Teresa Fernandez,Enrico Tortoli,Sarah E. Totten,Greg Tyrrell,Tuula Vasankari,Miguel Villar,Renata Walkiewicz,Kevin L. Winthrop,Dirk Wagner +66 more
TL;DR: A snapshot of NTM species distribution demonstrates that the species distribution among NTM isolates from pulmonary specimens in the year 2008 differed by continent and differed by country within these continents.
Journal ArticleDOI
Mycobacterium tuberculosis Strains with Highly Discordant Rifampin Susceptibility Test Results
A. Van Deun,Lucía Barrera,Ivan Bastian,Lanfranco Fattorini,Harald Hoffmann,K. M. Kam,Leen Rigouts,Sabine Rüsch-Gerdes,Abigail Wright +8 more
TL;DR: This study investigates the origin of highly discordant rifampin (rifampicin) (RMP) drug susceptibility test results obtained for Mycobacterium tuberculosis strains during proficiency testing to determine the frequency of these low-level-resistant isolates, and to identify technical improvements that may identify such strains.
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A retrospective TBNET assessment of linezolid safety, tolerability and efficacy in multidrug-resistant tuberculosis
G. B. Migliori,B. Eker,Morgan D Arcy Richardson,Giovanni Sotgiu,Jean-Pierre Zellweger,Alena Skrahina,J. Ortmann,Enrico Girardi,Harald Hoffmann,Giorgio Besozzi,Nazario Bevilacqua,Detlef Kirsten,Rosella Centis,Christoph Lange +13 more
TL;DR: Linezolid 600 mg q.d. added to an individualised multidrug regimen may improve the chance of bacteriological conversion, providing a better chance of treatment success in only the most complicated MDR/XDR-TB cases.
Journal ArticleDOI
Multidrug- and extensively drug-resistant tuberculosis
B. Eker,J. Ortmann,Giovanni Battista Migliori,Giovanni Sotgiu,R. Muetterlein,Rosella Centis,Harald Hoffmann,Detlef Kirsten,Tom Schaberg,Sabine Ruesch-Gerdes,Christoph Lange +10 more
TL;DR: In this paper, risk factors and treatment outcomes associated with multidrug-resistant (MDR) and extensively drug resistant (XDR) tuberculosis (TB) in Germany in 2004-2006 were evaluated.
Journal ArticleDOI
Identification of T-cell antigens specific for latent mycobacterium tuberculosis infection
Sebastian Schuck,Henrik Mueller,Frank Kunitz,Albert Neher,Harald Hoffmann,Kees L. C. M. Franken,Dirk Repsilber,Tom H. M. Ottenhoff,Stefan H. E. Kaufmann,Marc Jacobsen +9 more
TL;DR: An assay based on two rounds of in vitro restimulation and intracellular cytokine analysis that detects T-cell responses to antigens expressed during latent M. tuberculosis tuberculosis infection further support the hypothesis that the latency-associated antigen can be exploited as biomarkers for LTBI.