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Sebastian Schuck

Researcher at Heidelberg University

Publications -  41
Citations -  8941

Sebastian Schuck is an academic researcher from Heidelberg University. The author has contributed to research in topics: Endoplasmic reticulum & Unfolded protein response. The author has an hindex of 25, co-authored 41 publications receiving 8076 citations. Previous affiliations of Sebastian Schuck include Max Planck Society & University of California, San Francisco.

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Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition)

Daniel J. Klionsky, +2522 more
- 21 Jan 2016 - 
TL;DR: In this paper, the authors present a set of guidelines for the selection and interpretation of methods for use by investigators who aim to examine macro-autophagy and related processes, as well as for reviewers who need to provide realistic and reasonable critiques of papers that are focused on these processes.
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Resistance of cell membranes to different detergents

TL;DR: It is found that the detergents differ considerably in their ability to selectively solubilize membrane proteins and to enrich sphingolipids and cholesterol over glycerophospholipid as well as saturated over unsaturated phosphatidylcholine.
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Membrane expansion alleviates endoplasmic reticulum stress independently of the unfolded protein response

TL;DR: This work has shown that increasing the size of the ER by lipid synthesis helps the cell deal with ER stress.
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ER-phagy: selective autophagy of the endoplasmic reticulum.

TL;DR: This finding provides direct evidence that the ER can serve as a membrane source for autophagosome formation and indicates that ER-phagy could remove damaged or redundant parts of the ER and represent an important degradative functionality of the UPR that helps to afford homeostatic control.
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Polarized sorting in epithelial cells: raft clustering and the biogenesis of the apical membrane

TL;DR: The clustering of lipid rafts through the oligomerization of raft components could be utilized for segregating apical from basolateral cargo and for the generation of intracellular transport carriers.