H
Hargobinder Kaur
Researcher at Post Graduate Institute of Medical Education and Research
Publications - 19
Citations - 187
Hargobinder Kaur is an academic researcher from Post Graduate Institute of Medical Education and Research. The author has contributed to research in topics: Plasmodium vivax & Malaria. The author has an hindex of 7, co-authored 18 publications receiving 149 citations.
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Journal ArticleDOI
Design, synthesis and biological evaluation of chalconyl blended triazole allied organosilatranes as giardicidal and trichomonacidal agents
Gurjaspreet Singh,Aanchal Arora,Satinderpal Singh Mangat,Sunita Rani,Hargobinder Kaur,Kapil Goyal,Rakesh Sehgal,Indresh Kumar Maurya,Rupinder Tewari,Duane Choquesillo-Lazarte,Subash Chandra Sahoo,Navneet Kaur +11 more
TL;DR: A series of chalconyl blended triazole allied silatranes were synthesized in good yields using a simple, economical and biocompatible synthetic route and the entire library of compounds was found to be more active than metronidazole except 9a, 9f and 9g.
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Screening and identification of potential novel biomarker for diagnosis of complicated Plasmodium vivax malaria.
TL;DR: In silico analysis of the common targets of up-regulated miRNAs revealed UBA52 and hsa-miR-7977 as majorly regulated hubs in the PPI and mRNA–miRNA networks, suggesting their putative role in complicated P. vivax malaria.
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Metronidazole derivatives as a new class of antiparasitic agents: synthesis, prediction of biological activity, and molecular properties
Dua’ Y. Alawadi,Haythem A. Saadeh,Hargobinder Kaur,Kapil Goyal,Rakesh Sehgal,Taibi Ben Hadda,Naser A. ElSawy,Mohammad S. Mubarak +7 more
TL;DR: A series of new metronidazole urea and thiourea derivatives have been prepared in good yields through reactions of 2-(2-methyl-5-nitroimidazolyl) ethylamine hydrochloride with various cyanates and isothiocyanates.
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Synthesis and biological activity of novel amidrazones incorporating 5-nitroimidazole, ciprofloxacin, and 7-chloro-4-piperazinylquinoline
Haythem A. Saadeh,Haythem A. Saadeh,Khaled M. Al-Qaoud,Luay Abu-Qatouseh,Penelope Ahmad Shihab,Hargobinder Kaur,Kapil Goyal,Rakesh Sehgal,Mohammad S. Mubarak +8 more
TL;DR: Series of new amidrazones Ia-c, IIa–c, and IIIc, incorporating 5-nitroimidazole, ciprofloxacin, and 7-chloro-4-piperazinylquinoline moieties, were synthesized by reacting hydrazonoyl chlorides I–III with the proper amine in the presence of triethylamine to demonstrate strong anticancer activity and stronger antimicrobial potency.
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Development of Visually Improved Loop Mediated Isothermal Amplification for the Diagnosis of Plasmodium vivax Malaria in a Tertiary Hospital in Chandigarh, North India
TL;DR: In this article, the utility of visually improved loop-mediated isothermal amplification (LAMP) for the detection of Plasmodium vivax was evaluated targeting 18SrRNA gene in 145 microscopically confirmed P.vax and 20 Pivax negative patients.