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Heiko Braak

Researcher at University of Ulm

Publications -  352
Citations -  80226

Heiko Braak is an academic researcher from University of Ulm. The author has contributed to research in topics: Parkinson's disease & Neurofibrillary tangle. The author has an hindex of 110, co-authored 349 publications receiving 71061 citations. Previous affiliations of Heiko Braak include Katholieke Universiteit Leuven & University of Kiel.

Papers
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Journal ArticleDOI

Intraneuronal tau aggregation precedes diffuse plaque deposition, but amyloid-β changes occur before increases of tau in cerebrospinal fluid

Heiko Braak, +4 more
- 12 Jun 2013 - 
TL;DR: This viewpoint attempts to address questions arising in connection with this apparent sequential discrepancy in cerebrospinal fluid and questions and issues for which there are currently no clear-cut answers.
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Parenchymal and vascular Aβ-deposition and its effects on the degeneration of neurons and cognition in Alzheimer's disease

Dietmar Rudolf Thal, +2 more
- 01 Oct 2008 - 
TL;DR: The deposition of Aβ and the contribution of CAA to the degeneration of neurons and the clinical impact of A β and its therapeutic possibilities are studied.
Journal ArticleDOI

Parkinson’s disease: the thalamic components of the limbic loop are severely impaired by α-synuclein immunopositive inclusion body pathology

Udo Rüb, +6 more
- 01 Mar 2002 - 
TL;DR: The distribution and severity of PD-related inclusion body pathology was investigated in the thalamus of 12 autopsy cases with clinically diagnosed and neuropathologically confirmed PD by immunoreactions against the protein alpha-synuclein.
Journal ArticleDOI

Amyloid β-protein (Aβ)-containing astrocytes are located preferentially near N-terminal-truncated Aβ deposits in the human entorhinal cortex

Dietmar Rudolf Thal, +5 more
- 01 Jan 2000 - 
TL;DR: The results suggest that N-terminal-truncated Aβ peptide may be cleared preferentially from the extracellular space by astrocytic uptake and processing and point to the use of N- terminal truncation of Aβ in potential therapeutic strategies aimed at preventing the brain from amassing full-length Aβ deposits.
Book

Neuroanatomy and Pathology of Sporadic Alzheimer's Disease

Heiko Braak, +1 more
TL;DR: The staging hypothesis is based on the assumption that consistent and systematic changes in the distribution pattern of intraneuronal inclusions render staging possible.