H
Helen Mayles
Researcher at Clatterbridge Cancer Centre NHS Foundation Trust
Publications - 35
Citations - 2354
Helen Mayles is an academic researcher from Clatterbridge Cancer Centre NHS Foundation Trust. The author has contributed to research in topics: Radiation therapy & Dosimetry. The author has an hindex of 14, co-authored 35 publications receiving 1848 citations. Previous affiliations of Helen Mayles include University of Liverpool & National Health Service.
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Journal ArticleDOI
Conventional versus hypofractionated high-dose intensity-modulated radiotherapy for prostate cancer: 5-year outcomes of the randomised, non-inferiority, phase 3 CHHiP trial
David P. Dearnaley,Isabel Syndikus,Helen Mossop,Vincent Khoo,Alison Birtle,D. Bloomfield,John Graham,Peter Kirkbride,John P Logue,Zafar Malik,Julian Money-Kyrle,Joe M. O'Sullivan,Miguel Panades,Chris Parker,Helen Patterson,Christopher D Scrase,John Staffurth,Andrew Stockdale,Jean Tremlett,M. Bidmead,Helen Mayles,O. Naismith,C. South,Annie Gao,Clare Cruickshank,Shama Hassan,Julia Pugh,Clare Griffin,Emma Hall +28 more
TL;DR: Hypofractionated radiotherapy using 60 Gy in 20 fractions is non-inferior to conventional fractionation using 74 Gy in 37 fractions and is recommended as a new standard of care for external-beam radiotherapy of localised prostate cancer after 5 years follow-up.
Journal ArticleDOI
Partial-breast radiotherapy after breast conservation surgery for patients with early breast cancer (UK IMPORT LOW trial): 5-year results from a multicentre, randomised, controlled, phase 3, non-inferiority trial
Charlotte E. Coles,Clare Griffin,Anna M. Kirby,Jenny Titley,R.K. Agrawal,Abdulla Alhasso,I.S. Bhattacharya,A.M. Brunt,Laura Ciurlionis,Charlie Chan,Ellen M. Donovan,M. Emson,Adrian Harnett,Joanne S Haviland,Penelope Hopwood,Monica L Jefford,Ronald Kaggwa,Elinor J. Sawyer,Isabel Syndikus,Y. Tsang,Duncan Wheatley,Maggie Wilcox,John Yarnold,Judith M Bliss,Wail Al Sarakbi,Sarah Barber,Gillian C. Barnett,Peter Bliss,John Dewar,David J. Eaton,S. Ebbs,Ian O. Ellis,Philip M. Evans,Emma J. Harris,Hayley James,Cliona C. Kirwan,Julie Kirk,Helen Mayles,Anne McIntyre,J. Mills,A. Poynter,Elena Provenzano,Christine Rawlings,Mark Sculpher,Georges Sumo,M. Sydenham,Andrew Tutt,N. Twyman,K Venables,Anna Winship,John Winstanley,Gordon C. Wishart,Alastair M. Thompson +52 more
TL;DR: It is hypothesised that partial-breast radiotherapy restricted to the vicinity of the original tumour in women at lower than average risk of local relapse will improve the balance of beneficial versus adverse effects compared with whole-breasts radiotherapy.
Journal ArticleDOI
Conventional versus hypofractionated high-dose intensity-modulated radiotherapy for prostate cancer: preliminary safety results from the CHHiP randomised controlled trial
David P. Dearnaley,Isabel Syndikus,Georges Sumo,M. Bidmead,D. Bloomfield,Catharine H. Clark,Annie Gao,Shama Hassan,Alan Horwich,Robert Huddart,Vincent Khoo,Peter Kirkbride,Helen Mayles,P. Mayles,O. Naismith,Chris Parker,Helen Patterson,Martin J. Russell,Christopher D Scrase,C. South,John Staffurth,Emma Hall +21 more
TL;DR: A pre-planned preliminary safety analysis of side-effects in stages 1 and 2 of a randomised trial comparing standard and hypofractionated radiotherapy seems equally well tolerated as conventionally fractionated treatment at 2 years.
Journal ArticleDOI
The American Brachytherapy Society consensus guidelines for plaque brachytherapy of uveal melanoma and retinoblastoma
E. Rand Simpson,Brenda L. Gallie,Normand Laperrierre,Akbar Beiki-Ardakani,Tero Kivelä,Virpi Raivio,Jorma Heikkonen,Laurence Desjardins,Rémi Dendale,A. Mazal,Norbert Bornfeld,Wolfgang Sauerwein,D. Fluehs,Lorenzo Brualla,Santosh G Honavar,Vijay Anand P. Reddy,Shigenobu Suzuki,Naoya Murakami,S.V. Saakyan,Vladimir Valskiy,Anush Amiryan,Stefan Seregard,Charlotta All-Eriksson,Lars Hjelmqvist,Göran Lundell,Georges Sinclair,Marie Lundell,Bertil Damato,R Doug Errington,P. Mayles,Helen Mayles,Chris S. Bergstrom,Hans E. Grossniklaus,Ian R. Crocker,Elizabeth Butker,Matthew W. Wilson,Barrett G. Haik,Holger Geischen,Pradeep Patra,Jay S. Duker,John E. Mignano,Mark J. Rivard,Paul T. Finger,Ekaterina Semenova,Walter Choi,Nina Kalach +45 more
TL;DR: The American Brachytherapy Society (ABS) as mentioned in this paper developed a set of guidelines for plaque brachythermytherapy of choroidal melanoma and retinoblastoma.
Journal ArticleDOI
Local tumor control after 106Ru brachytherapy of choroidal melanoma
TL;DR: The low rate of local tumor recurrence suggests that ruthenium plaque radiotherapy is effective with good case selection and if special measures are taken to ensure that the plaque is positioned correctly.