P
P. Mayles
Researcher at Clatterbridge Cancer Centre NHS Foundation Trust
Publications - 13
Citations - 779
P. Mayles is an academic researcher from Clatterbridge Cancer Centre NHS Foundation Trust. The author has contributed to research in topics: Radiation therapy & Clinical endpoint. The author has an hindex of 8, co-authored 13 publications receiving 661 citations. Previous affiliations of P. Mayles include University of Liverpool.
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Journal ArticleDOI
Conventional versus hypofractionated high-dose intensity-modulated radiotherapy for prostate cancer: preliminary safety results from the CHHiP randomised controlled trial
David P. Dearnaley,Isabel Syndikus,Georges Sumo,M. Bidmead,D. Bloomfield,Catharine H. Clark,Annie Gao,Shama Hassan,Alan Horwich,Robert Huddart,Vincent Khoo,Peter Kirkbride,Helen Mayles,P. Mayles,O. Naismith,Chris Parker,Helen Patterson,Martin J. Russell,Christopher D Scrase,C. South,John Staffurth,Emma Hall +21 more
TL;DR: A pre-planned preliminary safety analysis of side-effects in stages 1 and 2 of a randomised trial comparing standard and hypofractionated radiotherapy seems equally well tolerated as conventionally fractionated treatment at 2 years.
Journal ArticleDOI
The American Brachytherapy Society consensus guidelines for plaque brachytherapy of uveal melanoma and retinoblastoma
E. Rand Simpson,Brenda L. Gallie,Normand Laperrierre,Akbar Beiki-Ardakani,Tero Kivelä,Virpi Raivio,Jorma Heikkonen,Laurence Desjardins,Rémi Dendale,A. Mazal,Norbert Bornfeld,Wolfgang Sauerwein,D. Fluehs,Lorenzo Brualla,Santosh G Honavar,Vijay Anand P. Reddy,Shigenobu Suzuki,Naoya Murakami,S.V. Saakyan,Vladimir Valskiy,Anush Amiryan,Stefan Seregard,Charlotta All-Eriksson,Lars Hjelmqvist,Göran Lundell,Georges Sinclair,Marie Lundell,Bertil Damato,R Doug Errington,P. Mayles,Helen Mayles,Chris S. Bergstrom,Hans E. Grossniklaus,Ian R. Crocker,Elizabeth Butker,Matthew W. Wilson,Barrett G. Haik,Holger Geischen,Pradeep Patra,Jay S. Duker,John E. Mignano,Mark J. Rivard,Paul T. Finger,Ekaterina Semenova,Walter Choi,Nina Kalach +45 more
TL;DR: The American Brachytherapy Society (ABS) as mentioned in this paper developed a set of guidelines for plaque brachythermytherapy of choroidal melanoma and retinoblastoma.
Journal ArticleDOI
Radiotherapy planning of the pelvis using distortion corrected MR images: the removal of system distortions.
TL;DR: Results are presented which show that the scanner and the phantoms used in measuring distortion give highly reproducible results with mean changes of the order of 0.1 mm between repeated measurements of marker positions in the same imaging session.
Journal ArticleDOI
Study protocol for the SARON trial: a multicentre, randomised controlled phase III trial comparing the addition of stereotactic ablative radiotherapy and radical radiotherapy with standard chemotherapy alone for oligometastatic non-small cell lung cancer
John Conibear,Brendan Chia,Yenting Ngai,Andrew Bates,Nicholas Counsell,R. Patel,David J. Eaton,Corinne Faivre-Finn,John D. Fenwick,Martin Forster,Gerard G Hanna,Susan Harden,P. Mayles,S. Moinuddin,David Landau +14 more
TL;DR: The SARON trial is a large, randomised controlled, multicentre, phase III trial for patients with oligometastatic EGFR, ALK and ROS1 mutation negative NSCLC to investigate the impact and feasibility of adding SABR/SRS and radical radiotherapy (RRT) following standard chemotherapy on OS.
Journal ArticleDOI
Toxicity and Patient-Reported Outcomes of a Phase 2 Randomized Trial of Prostate and Pelvic Lymph Node Versus Prostate only Radiotherapy in Advanced Localised Prostate Cancer (PIVOTAL)
David P. Dearnaley,Clare Griffin,Rebecca Lewis,P. Mayles,Helen Mayles,O. Naismith,V. Harris,Christopher D Scrase,John Staffurth,Isabel Syndikus,Anjali Zarkar,Daniel Ford,Yvonne Rimmer,Gail Horan,Vincent Khoo,John Frew,Ramachandran Venkitaraman,Emma Hall +17 more
TL;DR: PIVOTAL demonstrated that high-dose pelvic lymph node IMRT can be delivered at multiple centers with a modest side effect profile and the impact of P&P IMRT on disease control remains to be established.