H
Helena Pulido-Olmo
Researcher at Complutense University of Madrid
Publications - 8
Citations - 234
Helena Pulido-Olmo is an academic researcher from Complutense University of Madrid. The author has contributed to research in topics: Albuminuria & Arterial stiffness. The author has an hindex of 7, co-authored 8 publications receiving 180 citations.
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Journal ArticleDOI
Role of matrix metalloproteinase-9 in chronic kidney disease: a new biomarker of resistant albuminuria.
Helena Pulido-Olmo,Concha F. García-Prieto,Gloria Alvarez-Llamas,Maria G. Barderas,Fernando Vivanco,Isabel Aranguez,Beatriz Somoza,Julian Segura,Reinhold Kreutz,María S. Fernández-Alfonso,Luis M. Ruilope,Gema Ruiz-Hurtado +11 more
TL;DR: Increased circulating MMP-9 activity is associated with resistant albuminuria and a deleterious oxidative stress environment appears to be the underlying mechanism.
Journal ArticleDOI
Development of albuminuria and enhancement of oxidative stress during chronic renin-angiotensin system suppression.
Gema Ruiz-Hurtado,Luis Condezo-Hoyos,Helena Pulido-Olmo,Isabel Aranguez,Maria del Carmen González,Silvia M. Arribas,César Cerezo,Julian Segura,Manuel Praga,María S. Fernández-Alfonso,Luis M. Ruilope +10 more
TL;DR: It is concluded that albuminuria is accompanied by an amplified oxidative damage in patients in early stages of chronic kidney disease, indicating that chronic RAS protection must be directed to avoid development ofalbuminuria and oxidative damage.
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Mild and Short-Term Caloric Restriction Prevents Obesity-Induced Cardiomyopathy in Young Zucker Rats without Changing in Metabolites and Fatty Acids Cardiac Profile
Gema Ruiz-Hurtado,Concha F. García-Prieto,Helena Pulido-Olmo,Juan P. Velasco-Martín,Palmira Villa-Valverde,María Encarnación Fernández-Valle,Lisardo Boscá,María Fernández-Velasco,Javier Regadera,Beatriz Somoza,María S. Fernández-Alfonso +10 more
TL;DR: Mild and short-term CR prevented an obesity-induced cardiomyopathy phenotype in young obese fa/fa rats independently of the cardiac metabolic profile.
Journal ArticleDOI
Mild caloric restriction reduces blood pressure and activates endothelial AMPK-PI3K-Akt-eNOS pathway in obese Zucker rats.
Concha F. García-Prieto,Helena Pulido-Olmo,Gema Ruiz-Hurtado,Marta Gil-Ortega,Isabel Aranguez,Miguel A. Rubio,Mariano Ruiz-Gayo,Beatriz Somoza,María S. Fernández-Alfonso +8 more
TL;DR: Data show that mild short-term CR improves endothelial function and lowers blood pressure in obesity due to the activation of the AMPK-PI3K-Akt-eNOS pathway.
Journal ArticleDOI
Urinary alpha-1 antitrypsin and CD59 glycoprotein predict albuminuria development in hypertensive patients under chronic renin-angiotensin system suppression
Laura Gonzalez-Calero,Marta Martin-Lorenzo,Fernando de la Cuesta,Aroa S. Maroto,Montserrat Baldan-Martin,Gema Ruiz-Hurtado,Helena Pulido-Olmo,Julian Segura,Maria G. Barderas,Luis M. Ruilope,Fernando Vivanco,Gloria Alvarez-Llamas +11 more
TL;DR: Interestingly, CD59 and AAT are able to predict, in normoalbuminuric individuals, who will develop albuminuria in the future, being potential predictors of vascular damage and CV risk.