H
Helle Hvilsted Nielsen
Researcher at University of Southern Denmark
Publications - 72
Citations - 2934
Helle Hvilsted Nielsen is an academic researcher from University of Southern Denmark. The author has contributed to research in topics: Medicine & Internal medicine. The author has an hindex of 24, co-authored 61 publications receiving 2475 citations. Previous affiliations of Helle Hvilsted Nielsen include Odense University Hospital.
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Journal ArticleDOI
Risk of dementia in Parkinson’s disease: A community-based, prospective study
Dag Aarsland,Kjeld Andersen,Jan Petter Larsen,A. Lolk,Helle Hvilsted Nielsen,Per Kragh-Sørensen +5 more
TL;DR: Patients with PD have an almost sixfold increased risk for becoming demented compared with subjects without PD.
Journal ArticleDOI
Microglia protect neurons against ischemia by synthesis of tumor necrosis factor.
Kate Lykke Lambertsen,Bettina Hjelm Clausen,Alicia A. Babcock,Rikke Gregersen,Christina Fenger,Helle Hvilsted Nielsen,Laila Skov Haugaard,Martin Wirenfeldt,Marianne Nielsen,Frederik Dagnæs-Hansen,Horst Bluethmann,Nils J. Færgeman,Michael Meldgaard,Tomas Deierborg,Bente Finsen +14 more
TL;DR: It is reported that TNF deficiency is associated with reduced microglial population size and Toll-like receptor 2 expression in unmanipulated brain, which might also influence the neuronal response to injury.
Journal ArticleDOI
Multicentre comparison of a diagnostic assay: aquaporin-4 antibodies in neuromyelitis optica
Patrick Waters,Markus Reindl,Albert Saiz,Kathrin Schanda,Friederike Tuller,Vlastimil Král,Petra Nytrova,Ondrej Sobek,Helle Hvilsted Nielsen,Torben Barington,Søren Thue Lillevang,Zsolt Illes,Kristin Rentzsch,Achim Berthele,Timea Berki,Letizia Granieri,Antonio Bertolotto,Bruno Giometto,Luigi Zuliani,Dörte Hamann,E Daniëlle van Pelt,Rogier Q. Hintzen,Romana Höftberger,Romana Höftberger,Carme Martínez Costa,Manuel Comabella,Xavier Montalban,Mar Tintoré,Aksel Siva,Ayse Altintas,Günnur Deniz,Mark Woodhall,Jacqueline Palace,Friedemann Paul,Hans-Peter Hartung,Orhan Aktas,Sven Jarius,Brigitte Wildemann,Christian A. Vedeler,Christian A. Vedeler,Anne Ruiz,M. Isabel Leite,Peter Trillenberg,Monika Probst,Sandra Saschenbrecker,Angela Vincent,Romain Marignier +46 more
TL;DR: The cell-based assays were most sensitive and specific overall, but immunohistochemistry or flow cytometry could be equally accurate in specialist centres.
Journal ArticleDOI
Toll-like receptor 2 signaling in response to brain injury: an innate bridge to neuroinflammation.
Alicia A. Babcock,Martin Wirenfeldt,Thomas Hellesøe Holm,Helle Hvilsted Nielsen,Lasse Dissing-Olesen,Henrik Toft-Hansen,Jason M. Millward,Regine Landmann,Serge Rivest,Bente Finsen,Trevor Owens +10 more
TL;DR: A role for TLR2 signaling is identified in the early glial response to brain injury, acting as an innate bridge to neuroinflammation.
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Treatment for Helicobacter pylori infection and risk of Parkinson's disease in Denmark.
TL;DR: It has been speculated that gastrointestinal infection with Helicobacter pylori contributes to the development of Parkinson’s disease, and nationwide Danish registers were used to investigate this hypothesis.