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Anne Ruiz
Researcher at French Institute of Health and Medical Research
Publications - 20
Citations - 1417
Anne Ruiz is an academic researcher from French Institute of Health and Medical Research. The author has contributed to research in topics: Neuromyelitis optica & Aquaporin 4. The author has an hindex of 12, co-authored 17 publications receiving 994 citations. Previous affiliations of Anne Ruiz include University of Lyon & Lyon College.
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Journal ArticleDOI
Clinical spectrum and prognostic value of CNS MOG autoimmunity in adults: The MOGADOR study.
Alvaro Cobo-Calvo,Anne Ruiz,Elisabeth Maillart,Bertrand Audoin,Hélène Zéphir,Bertrand Bourre,Jonathan Ciron,Nicolas Collongues,David Brassat,François Cotton,Caroline Papeix,Françoise Durand-Dubief,David Laplaud,Romain Deschamps,Mikael Cohen,Damien Biotti,Xavier Ayrignac,Caroline Tilikete,Eric Thouvenot,Bruno Brochet,Cécile Dulau,Thibault Moreau,Ayman Tourbah,Pierre Lebranchu,Laure Michel,Christine Lebrun-Frenay,Alexis Montcuquet,Guillaume Mathey,Marc Debouverie,Jean Pelletier,Pierre Labauge,Nathalie Derache,M. Coustans,Fabien Rollot,Jérôme De Seze,Sandra Vukusic,Romain Marignier +36 more
TL;DR: In adults, MOG-Ab-associated disease extends beyond clinical and radiologic abnormalities in the optic nerve and spinal cord and despite the relapsing course, the overall visual and motor outcome is better compared with AQP4- Ab-positive patients.
Journal ArticleDOI
Inflammatory monocytes activate memory CD8(+) T and innate NK lymphocytes independent of cognate antigen during microbial pathogen invasion
TL;DR: Inflammatory monocyte-derived IL-18 and IL-15 are critical to initiate memory CD8(+) T and NK lymphocytes differentiation into antimicrobial effector cells.
Journal ArticleDOI
Multicentre comparison of a diagnostic assay: aquaporin-4 antibodies in neuromyelitis optica
Patrick Waters,Markus Reindl,Albert Saiz,Kathrin Schanda,Friederike Tuller,Vlastimil Král,Petra Nytrova,Ondrej Sobek,Helle Hvilsted Nielsen,Torben Barington,Søren Thue Lillevang,Zsolt Illes,Kristin Rentzsch,Achim Berthele,Timea Berki,Letizia Granieri,Antonio Bertolotto,Bruno Giometto,Luigi Zuliani,Dörte Hamann,E Daniëlle van Pelt,Rogier Q. Hintzen,Romana Höftberger,Romana Höftberger,Carme Martínez Costa,Manuel Comabella,Xavier Montalban,Mar Tintoré,Aksel Siva,Ayse Altintas,Günnur Deniz,Mark Woodhall,Jacqueline Palace,Friedemann Paul,Hans-Peter Hartung,Orhan Aktas,Sven Jarius,Brigitte Wildemann,Christian A. Vedeler,Christian A. Vedeler,Anne Ruiz,M. Isabel Leite,Peter Trillenberg,Monika Probst,Sandra Saschenbrecker,Angela Vincent,Romain Marignier +46 more
TL;DR: The cell-based assays were most sensitive and specific overall, but immunohistochemistry or flow cytometry could be equally accurate in specialist centres.
Journal ArticleDOI
Evaluation of treatment response in adults with relapsing MOG-Ab-associated disease
Alvaro Cobo-Calvo,Maria Sepúlveda,Fabien Rollot,Thaís Armangue,Anne Ruiz,Elisabeth Maillart,Caroline Papeix,Bertrand Audoin,Hélène Zéphir,Damien Biotti,Jonathan Ciron,Françoise Durand-Dubief,Nicolas Collongues,Xavier Ayrignac,Pierre Labauge,Eric Thouvenot,Bertrand Bourre,Alexis Montcuquet,Mikael Cohen,Romain Deschamps,Nuria Sola-Valls,Sara Llufriu,Jérôme De Seze,Yolanda Blanco,Sandra Vukusic,Albert Saiz,Romain Marignier +26 more
TL;DR: In adults with relapsing MOG-Ab-associated disease, immunosuppressant therapy (azathioprine, MMF and rituximab) is associated with reduced risk of relapse and better disability outcomes and such an effect was not found in the few patients treated with MS-DMD.
Journal ArticleDOI
MOG antibody-related disorders: common features and uncommon presentations.
Alvaro Cobo-Calvo,Anne Ruiz,Hyacintha d'Indy,Anne-Lise Poulat,Maryline Carneiro,Nicolas Philippe,Françoise Durand-Dubief,Kumaran Deiva,Sandra Vukusic,Vincent Desportes,Romain Marignier +10 more
TL;DR: MOG-Ab-related disorders shared common clinical and prognostic features, but encompass a spectrum wider than recently reported, and unusual presentations were identified in three patients: patchy spinal cord gadolinium-enhancing lesions, an associated teratoma, and one presented with status epilepticus.