C
Christina Fenger
Researcher at University of Southern Denmark
Publications - 40
Citations - 1532
Christina Fenger is an academic researcher from University of Southern Denmark. The author has contributed to research in topics: Epilepsy & Medicine. The author has an hindex of 16, co-authored 28 publications receiving 1177 citations.
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Journal ArticleDOI
Microglia protect neurons against ischemia by synthesis of tumor necrosis factor.
Kate Lykke Lambertsen,Bettina Hjelm Clausen,Alicia A. Babcock,Rikke Gregersen,Christina Fenger,Helle Hvilsted Nielsen,Laila Skov Haugaard,Martin Wirenfeldt,Marianne Nielsen,Frederik Dagnæs-Hansen,Horst Bluethmann,Nils J. Færgeman,Michael Meldgaard,Tomas Deierborg,Bente Finsen +14 more
TL;DR: It is reported that TNF deficiency is associated with reduced microglial population size and Toll-like receptor 2 expression in unmanipulated brain, which might also influence the neuronal response to injury.
Journal ArticleDOI
Microglial cell population dynamics in the injured adult central nervous system.
Rune Ladeby,Martin Wirenfeldt,Daniel Garcia-Ovejero,Christina Fenger,Lasse Dissing-Olesen,Ishar Dalmau,Bente Finsen +6 more
TL;DR: The demonstration of an injury-enhanced recruitment of bone marrow-derived cells into the perforant path-denervated dentate gyrus, raises the possibility of using genetically manipulated cells as vectors for lesion-site-specific gene therapy even in minimally injured areas of the central nervous system.
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Expression and Role of CXCL10 during the Encephalitic Stage of Experimental and Clinical African Trypanosomiasis
Daniel Ndem Amin,Martin E. Rottenberg,Allan Randrup Thomsen,Dieudonné Mumba,Christina Fenger,Krister Kristensson,Philippe Büscher,Bente Finsen,Willias Masocha +8 more
TL;DR: Levels of CXCL10 in patients with late stage human African trypanosomiasis were associated with somnolence, low body weight, andtrypanosomes in the cerebrospinal fluid.
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CD8+ T cells complement antibodies in protecting against yellow fever virus.
Maria Rosaria Bassi,Michael Kongsgaard,Maria Abildgaard Steffensen,Christina Fenger,Michael R. Rasmussen,Karsten Skjødt,Bente Finsen,Anette Stryhn,Søren Buus,Jan Pravsgaard Christensen,Allan Randrup Thomsen +10 more
TL;DR: This study observed an accelerated T cell influx into the brain after intracerebral challenge of vaccinated mice, and this T cell recruitment correlated with improved virus control in the brain, and was the first time that YF-specific CD8+ T cells have been demonstrated to possess antiviral activity in vivo.
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Biological concepts in human sodium channel epilepsies and their relevance in clinical practice.
Andreas Brunklaus,Juanjiangmeng Du,Felix Steckler,Ismael I. Ghanty,Katrine M. Johannesen,Christina Fenger,Stephanie Schorge,David Baez-Nieto,Haoran Wang,Andrew J. Allen,Jen Q. Pan,Holger Lerche,Henrike O. Heyne,Henrike O. Heyne,Henrike O. Heyne,Joseph D. Symonds,Sameer M. Zuberi,Stephen Sanders,Beth Rosen Sheidley,Dana Craiu,Heather E. Olson,Sarah Weckhuysen,Peter DeJonge,Ingo Helbig,Hilde Van Esch,Tiffany Busa,Matthieu Milh,Bertrand Isidor,Christel Depienne,Annapurna Poduri,Annapurna Poduri,Arthur J. Campbell,Jordane Dimidschstein,Rikke S. Møller,Dennis Lal +34 more
TL;DR: To better understand the biology of seizure susceptibility in SCN‐related epilepsies, the aim was to determine similarities and differences between sodium channel disorders, allowing a broader perspective on precision treatment than on an individual gene level alone.