Hennie R. Hoogenboom

TL;DR: The human anti-HLA-A 1-MAGE-A1 antibody described here may prove very useful for monitoring the cell surface expression of these complexes, and eventually, as a targeting reagent for the specific immunotherapy of HLA- a1 patients bearing a MAGE-a1-positive tumor.

TL;DR: The studies suggest that it is feasible to create specific single VL domains to diverse targets as is the case for single VH domains, and may form the basis of a new family of immunomodulatory recombinant molecules.

TL;DR: The rationale of this study was to select a non‐immune phage displayed human antibody library on peptides designed from the coding regions of the gene sequences and to verify whether such antibodies would be suitable probes for the parental protein in immunohistochemical and Western blot analysis.

TL;DR: The results show that, although cells can be used as antigen carriers to select and screen phage antibodies, the nature of the antigen target has a profound effect on the outcome of the selection.

TL;DR: A review of the current status of the display and selection of cDNA libraries using phage, and the construction of a set of phage display vectors suitable for cDNA display based on fusion to the minor bacteriophage coat protein 6 (pVI) of filamentous phage.