H
Henriette van Praag
Researcher at Florida Atlantic University
Publications - 58
Citations - 5402
Henriette van Praag is an academic researcher from Florida Atlantic University. The author has contributed to research in topics: Neurogenesis & Dentate gyrus. The author has an hindex of 31, co-authored 52 publications receiving 4264 citations. Previous affiliations of Henriette van Praag include Allen Institute for Brain Science & National Institutes of Health.
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Bridging animal and human models of exercise-induced brain plasticity.
TL;DR: In this paper, the influence of exercise on hippocampal structure and function, addressing common themes such as spatial memory and pattern separation, brain structure and plasticity, neurotrophic factors, and vasculature.
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Combined adult neurogenesis and BDNF mimic exercise effects on cognition in an Alzheimer’s mouse model
Se Hoon Choi,Enjana Bylykbashi,Zena K. Chatila,Star W. Lee,Benjamin Pulli,Gregory D. Clemenson,Eunhee Kim,Alexander Rompala,Mary K. Oram,Caroline Asselin,Jenna Aronson,Can Zhang,Sean J. Miller,Andrea N. Lesinski,John W. Chen,Doo Yeon Kim,Henriette van Praag,Bruce M. Spiegelman,Fred H. Gage,Rudolph E. Tanzi +19 more
TL;DR: Exercise-induced AHN improved cognition along with reduced Aβ load and increased levels of brain-derived neurotrophic factor (BDNF), interleukin-6 (IL-6), fibronectin type III domain–containing protein–5 (FNDC5), and synaptic markers, however, AHN activation was also required for exercise-induced improvement in memory.
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When Neurogenesis Encounters Aging and Disease
TL;DR: Evidence that a reduction in neurogenesis underlies aging-related cognitive deficits and impairments in disorders such as Alzheimer's disease is considered, and knowledge of the underlying neurogenic signaling pathways could lead to novel therapeutic strategies for preserving brain function.
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Running is the neurogenic and neurotrophic stimulus in environmental enrichment
TL;DR: It is concluded that exercise is the critical factor mediating increased BDNF levels and adult hippocampal neurogenesis, and new cell proliferation, survival, neuron number, and neurotrophin levels were enhanced only when running was accessible.
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Running-Induced Systemic Cathepsin B Secretion Is Associated with Memory Function.
Hyo Youl Moon,Andreas Becke,David Berron,Benjamin Becker,Nirnath Sah,Galit Benoni,Emma Janke,Susan T. Lubejko,Nigel H. Greig,Julie A. Mattison,Emrah Düzel,Emrah Düzel,Henriette van Praag +12 more
TL;DR: It is shown that a muscle secretory factor, cathepsin B (CTSB) protein, is important for the cognitive and neurogenic benefits of running, and CTSB as a mediator of effects of exercise on cognition is suggested.