[신간의 별자리x] 우리/미술, 그리고 ‘슬픔의 박물관’

2. Essential Components: Earlier Developments 5449 2.1. Activated alkenes/alkynes 5450 2.1.1. Acyclic activated alkenes/ alkynes 5450 2.1.2. Cyclic activated alkenes 5451 2.2. Electrophiles 5451 2.3. Catalysts 5452 3. Essential Components: Recent Developments 5452 3.1. Activated Alkenes/Alkynes 5452 3.2. Electrophiles 5460 3.3. Catalysts 5477 4. Asymmetric Baylis-Hillman Reaction: Earlier Developments 5495

Recent contributions from the Baylis-Hillman reaction to organic chemistry.

The union of photoredox and nickel catalysis has resulted in a renaissance in radical chemistry as well as in the use of nickel-catalyzed transformations, specifically for carbon-carbon bond formation. Collectively, these advances address the longstanding challenge of late-stage cross-coupling of functionalized alkyl fragments. Empowered by the notion that photocatalytically generated alkyl radicals readily undergo capture by Ni complexes, wholly new feedstocks for cross-coupling have been realized. Herein, we highlight recent developments in several types of alkyl cross-couplings that are accessible exclusively through this approach.

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Alkyl Carbon-Carbon Bond Formation by Nickel/Photoredox Cross-Coupling.

Bromination is one of the most important transformations in organic synthesis and can be carried out using bromine and many other bromo compounds. Use of molecular bromine in organic synthesis is well-known. However, due to the hazardous nature of bromine, enormous growth has been witnessed in the past several decades for the development of solid bromine carriers. This review outlines the use of bromine and different bromo-organic compounds in organic synthesis. The applications of bromine, a total of 107 bromo-organic compounds, 11 other brominating agents, and a few natural bromine sources were incorporated. The scope of these reagents for various organic transformations such as bromination, cohalogenation, oxidation, cyclization, ring-opening reactions, substitution, rearrangement, hydrolysis, catalysis, etc. has been described briefly to highlight important aspects of the bromo-organic compounds in organic synthesis.

Use of Bromine and Bromo-Organic Compounds in Organic Synthesis

"Comprehensive Heterocyclic Chemistry" was published in 1984 and is now available on CD-ROM.

Comprehensive heterocyclic chemistry on CD-ROM

Iron(III) trifluoroacetate and trifluoromethanesulfonate: Recyclable Lewis acid catalysts for one-pot synthesis of 3,4-dihydropyrimidinones or their sulfur analogues and 1,4-dihydropyridines via solvent-free Biginelli and Hantzsch condensation protocols

Article history: Received March 20, 2013 Received in Revised form July 7, 2013 Accepted 10 July 2013 Available online 12 July 2013 An efficient, green, and facile four-component reaction for the preparation of pyrano[2,3c]pyrazole derivatives through the condensation reaction of aryl aldehydes, ethyl acetoacetate, malononitrile, and hydrazine hydrate or phenyl hydrazine in the presence of commercially available organocatalyst sodium benzoate under aqueous condition is reported. The products are produced with high yields and in shorter reaction times. It also is mild, safe, green and environmental friendly. © 2013 Growing Science Ltd. All rights reserved.

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One-pot, four-component synthesis of pyrano(2,3-c)pyrazoles catalyzed by sodium benzoate in aqueous medium

An efficient synthesis of 5-benzoyloxazolines by regio- and stereo-controlled reaction of N-substituted 2-benzoylaziridines under microwave irradiation

An efficient one-pot three component method was developed for the synthesis of highly substituted 2-iminothizolines by the reaction of isothiocyanates, primary amines and α-bromoketones in ambient temperature. The reaction produced the desired products in a completely regioselective manner in excellent yields (78-94%).

A convenient one-pot three component approach to synthesis of highly substituted iminothiazolines

Ring expansion of keto aziridines to the corresponding 2,5-diaryl oxazoles in the presence of dicyclohexyl carbodiimide and iodine under refluxing acetonitrile conditions is described. A plausible mechanism is proposed.

Heshmat Allah Samimi

Papers

Iron(III) trifluoroacetate and trifluoromethanesulfonate: Recyclable Lewis acid catalysts for one-pot synthesis of 3,4-dihydropyrimidinones or their sulfur analogues and 1,4-dihydropyridines via solvent-free Biginelli and Hantzsch condensation protocols

One-pot, four-component synthesis of pyrano(2,3-c)pyrazoles catalyzed by sodium benzoate in aqueous medium

An efficient synthesis of 5-benzoyloxazolines by regio- and stereo-controlled reaction of N-substituted 2-benzoylaziridines under microwave irradiation

A convenient one-pot three component approach to synthesis of highly substituted iminothiazolines

A New Approach to Ring Expansion of Keto Aziridines to 2,5-Diaryloxazoles