H
Hidekachi Kurotaki
Researcher at Hirosaki University
Publications - 48
Citations - 820
Hidekachi Kurotaki is an academic researcher from Hirosaki University. The author has contributed to research in topics: Vimentin & DNA methylation. The author has an hindex of 14, co-authored 45 publications receiving 713 citations.
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Journal ArticleDOI
Interferon-γ stimulates the expression of galectin-9 in cultured human endothelial cells
Tadaatsu Imaizumi,Mika Kumagai,Naoko Sasaki,Hidekachi Kurotaki,Fumiaki Mori,Masako Seki,Nozomu Nishi,Koji Fujimoto,Kunikazu Tanji,Takeo Shibata,Wakako Tamo,Tomoh Matsumiya,Hidemi Yoshida,Xue-Fan Cui,Shingo Takanashi,Katsumi Hanada,Ken Okumura,Soroku Yagihashi,Koichi Wakabayashi,Takanori Nakamura,Mitsuomi Hirashima,Kei Satoh +21 more
TL;DR: IFN‐γ‐induced production of galectin‐9 by endothelial cells may play an important role in immune responses by regulating interactions between the vascular wall and eosinophils.
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Apoptosis, bcl-2 expression and p53 accumulation in myelodysplastic syndrome, myelodysplastic-syndrome-derived acute myelogenous leukemia and de novo acute myelogenous leukemia.
TL;DR: It is suggested that the suppression of apoptosis associated with enhanced bcl-2 expression and p53 accumulation increases the probability of developing leukemia in MDS, and that oncogenetic development might be different between MDS-derived AML and de novo AML.
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Transgenic expression of BACH1 transcription factor results in megakaryocytic impairment
Tsutomu Toki,Fumiki Katsuoka,Rika Kanezaki,Gang Xu,Hidekachi Kurotaki,Jiying Sun,Takuya Kamio,Seiji Watanabe,Satoru Tandai,Kiminori Terui,Soroku Yagihashi,Norio Komatsu,Kazuhiko Igarashi,Masayuki Yamamoto,Etsuro Ito +14 more
TL;DR: Evidence is provided that BACH1 acts as a transcriptional repressor in the regulation of MARE-dependent genes in megakaryocytes, and binds to the thromboxane synthase gene, one of the target genes for p45 in megAKaryocytes.
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Filamentous aggregations of phosphorylated α-synuclein in Schwann cells (Schwann cell cytoplasmic inclusions) in multiple system atrophy
Keiko Nakamura,Keiko Nakamura,Fumiaki Mori,Tomoya Kon,Kunikazu Tanji,Yasuo Miki,Masahiko Tomiyama,Hidekachi Kurotaki,Yasuko Toyoshima,Akiyoshi Kakita,Hitoshi Takahashi,Masahito Yamada,Koichi Wakabayashi +12 more
TL;DR: The present findings indicate that Schwann cells are also involved in the disease process of MSA.
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Accumulation of phosphorylated α-synuclein in subpial and periventricular astrocytes in multiple system atrophy of long duration.
Keiko Nakamura,Keiko Nakamura,Fumiaki Mori,Tomoya Kon,Kunikazu Tanji,Yasuo Miki,Masahiko Tomiyama,Hidekachi Kurotaki,Yasuko Toyoshima,Akiyoshi Kakita,Hitoshi Takahashi,Masahito Yamada,Koichi Wakabayashi +12 more
TL;DR: Immunohistochemically examined the frontal and temporal lobes, basal ganglia, cerebellum, brainstem and spinal cord of patients with MSA and Lewy body disease, and also in control subjects, and revealed that the phosphorylated α‐synuclein‐immunoreactive structures in astrocytes were non‐fibrillar and associated with granular and vesicular structures.