Hilda Lomelí

TL;DR: Molecular cloning identified three complementary DNA species of rat brain, encoding NMDA receptor subunits NMDAR2A (NR2A), NR2B, and NR2C, which are 55 to 70% ientical in sequence, and these are structurally related, with less than 20% sequence identity, to other excitatory amino acid receptor sub Units.

TL;DR: Site-selective nuclear RNA editing controls the calcium permeability of AMPA receptor channels, and RNA editing at a second site is shown here to affect the kinetic aspects of these channels in rat brain.

TL;DR: A previously unknown function of Oct4 in maintaining viability of mammalian germline is suggested using the conditional Cre/loxP gene targeting strategy to assess Oct4 function in primordial germ cells (PGCs).

TL;DR: This double-reporter transgenic line is able to indicate the occurrence of Cre excision in an extremely widespread manner from early embryonic to adult lineages and will be a valuable reagent for the increasing number of investigators taking advantage of the powerful tools provided by the Cre/loxP site-specific recombinase system.

TL;DR: The rat delta‐2 gene is expressed predominantly in Purkinje cells of the cerebellum whereas only low levels of delta‐1 transcripts are found in the adult brain, with particularly high mRNA levels in the caudate putamen of late embryonic/early postnatal stages.