H
Hirohito Metoki
Researcher at Tohoku Pharmaceutical University
Publications - 326
Citations - 12676
Hirohito Metoki is an academic researcher from Tohoku Pharmaceutical University. The author has contributed to research in topics: Blood pressure & Population. The author has an hindex of 47, co-authored 276 publications receiving 10877 citations. Previous affiliations of Hirohito Metoki include Japan Society for the Promotion of Science & Tohoku University.
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Journal ArticleDOI
Efficacy and duration of action of the four selective angiotensin II subtype 1 receptor blockers, losartan, candesartan, valsartan and telmisartan, in patients with essential hypertension determined by home blood pressure measurements.
Takuya Nishimura,Junichiro Hashimoto,Takayoshi Ohkubo,Masahiro Kikuya,Hirohito Metoki,Kei Asayama,Kazuhito Totsune,Yutaka Imai +7 more
TL;DR: The efficacy and duration of action of 4 angiotensin II receptor blockers (ARBs) in patients with essential hypertension using self-measurement of blood pressure at home and to examine the differential effect of the four ARBs on home pulse pressure were compared.
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Stroke risk in treated hypertension based on home blood pressure: The ohasama study
Daisaku Yasui,Kei Asayama,Takayoshi Ohkubo,Masahiro Kikuya,Atsuhiro Kanno,Azusa Hara,Takuo Hirose,Taku Obara,Hirohito Metoki,Ryusuke Inoue,Kazuhito Totsune,Haruhisa Hoshi,Hiroshi Satoh,Yutaka Imai +13 more
TL;DR: Home BP is a better tool to assess stroke risk, especially in treated hypertensives, as suggested by a strong association between elevated home BP and increased risk of stroke.
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Masked hypertension determined by self-measured blood pressure at home and chronic kidney disease in the Japanese general population: the Ohasama study.
Hiroyuki Terawaki,Hirohito Metoki,Hirohito Metoki,Masaaki Nakayama,Takayoshi Ohkubo,Masahiro Kikuya,Kei Asayama,Ryusuke Inoue,Haruhisa Hoshi,Sadayoshi Ito,Yutaka Imai +10 more
TL;DR: MHT, like SHT, is closely related to CKD, and HBP measurement could be a useful screening strategy to detect CKD in the general population.
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Night-time blood pressure is associated with the development of chronic kidney disease in a general population: the Ohasama Study.
Atsuhiro Kanno,Masahiro Kikuya,Kei Asayama,Michihiro Satoh,Ryusuke Inoue,Miki Hosaka,Hirohito Metoki,Taku Obara,Haruhisa Hoshi,Kazuhito Totsune,Toshinobu Sato,Yoshio Taguma,Hiroshi Sato,Yutaka Imai,Takayoshi Ohkubo +14 more
TL;DR: Night-time BP is a better predictor of CKD development than daytime BP in the general population and is considered useful for evaluating the risk of progression to CKD.
Journal ArticleDOI
Increased expression of (pro)renin receptor in the remnant kidneys of 5/6 nephrectomized rats
Takuo Hirose,Nobuyoshi Mori,Kazuhito Totsune,Ryo Morimoto,Takahiro Maejima,Takuya Kawamura,Hirohito Metoki,Kei Asayama,Masahiro Kikuya,Takayoshi Ohkubo,Masahiro Kohzuki,Kazuhiro Takahashi,Yutaka Imai +12 more
TL;DR: Findings indicate that the intra-renal (P)RR expression is increased in the remnant kidneys of 5/6 nephrectomized rats, and suggest that ( P)RR may contribute to the renal injury.