H
Hirohito Metoki
Researcher at Tohoku Pharmaceutical University
Publications - 326
Citations - 12676
Hirohito Metoki is an academic researcher from Tohoku Pharmaceutical University. The author has contributed to research in topics: Blood pressure & Population. The author has an hindex of 47, co-authored 276 publications receiving 10877 citations. Previous affiliations of Hirohito Metoki include Japan Society for the Promotion of Science & Tohoku University.
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Journal ArticleDOI
Genetic polymorphisms in the beta-subunit of the epithelial sodium channel (βENaC) gene in the Japanese population.
Michiko Suzuki,Tomomi Sato,Tohru Fujiwara,Mari Michimata,Tsutomu Araki,Hirohito Metoki,Masahiro Kikuya,Itsuro Kazama,Junichiro Hashimoto,Atsushi Hozawa,Takayoshi Ohkubo,Ichiro Tsuji,Yutaka Imai,Mitsunobu Matsubara +13 more
TL;DR: Clinical features in those with the V434M mutation suggest the presence of physiological effects of this mutation on plasma sodium regulation, and genetic polymorphisms of βENaC in the Japanese population were determined.
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Low birth weight and abnormal pre-pregnancy body mass index were at higher risk for hypertensive disorders of pregnancy
Maiko Wagata,Mami Ishikuro,Taku Obara,Masato Nagai,Satoshi Mizuno,Naoki Nakaya,Tomohiro Nakamura,Takumi Hirata,Naho Tsuchiya,Hirohito Metoki,Soichi Ogishima,Atsushi Hozawa,Kengo Kinoshita,Shigeo Kure,Nobuo Yaegashi,Masayuki Yamamoto,Shinichi Kuriyama,Junichi Sugawara +17 more
TL;DR: A significant association with HDP was found for women born with a low birth weight who were underweight or overweight as adults in Japanese women, and maintaining a normal weight may be effective for preventing HDP even if a woman was born small.
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Consideration of the reference value and number of measurements of the urinary sodium-to-potassium ratio based on the prevalence of untreated home hypertension: TMM Cohort Study
Mana Kogure,Tomohiro Nakamura,Naho Tsuchiya,Takumi Hirata,Kotaro Nochioka,Akira Narita,Rieko Hatanaka,F. Itabashi,I. Kanno,Taku Obara,Michihiro Satoh,Hirohito Metoki,Ken Miyagawa,Hiroshi Koshimizu,Sho Nagayoshi,Akira Uruno,Masahiro Kikuya,Kichiya Suzuki,Naoki Nakaya,Junichi Sugawara,Shinichi Kuriyama,Ichiro Tsuji,Shigeo Kure,Atsushi Hozawa +23 more
TL;DR: In this article , the authors investigated the number of days required to yield a better association between the morning uNa/K ratio and home BP (HBP) and determined a morning una/k ratio value that can be used as a reference value in participants who are not taking antihypertensive medication.
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Social isolation and insomnia among pregnant women in Japan: The Tohoku Medical Megabank Project Birth and Three-Generation Cohort Study.
Keiko Murakami,Mami Ishikuro,Taku Obara,Fumihiko Ueno,Aoi Noda,Tomomi Onuma,Fumiko Matsuzaki,Saya Kikuchi,Natsuko Kobayashi,Hirotaka Hamada,Noriyuki Iwama,Hirohito Metoki,Masahiro Kikuya,Masatoshi Saito,Junichi Sugawara,Hiroaki Tomita,Nobuo Yaegashi,Shinichi Kuriyama +17 more
TL;DR: In this article , a cross-sectional study was conducted to estimate the prevalence of insomnia and examine the association between social isolation and insomnia among pregnant women, which was part of the Tohoku Medical Megabank Project Birth and Three-Generation Cohort Study from 2013 to 2017.
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The A118G single-nucleotide polymorphism in OPRM1 is a risk factor for asthma severity.
Kaori Kawakami,Tomomitsu Miyasaka,Yutaka Nakamura,Hirohito Metoki,Satoshi Miyata,Miki Sato,Ichiro Sora,Kohei Yamauchi,Kazuyoshi Kawakami,Julie A. Blendy,Tasuku Kawano,Hiroaki Shimokawa,Motoaki Takayanagi,Isao Ohno,Tomoko Takahashi +14 more
TL;DR: In this article, the authors evaluated the genetic influence of a functional single-nucleotide polymorphism (SNP) in the stress-related μ-opioid receptor gene (OPRM1; A118G SNP, rs1799971) on asthma severity.