H
Hirokazu Murakami
Researcher at Gunma University
Publications - 277
Citations - 3558
Hirokazu Murakami is an academic researcher from Gunma University. The author has contributed to research in topics: Multiple myeloma & Leukemia. The author has an hindex of 28, co-authored 268 publications receiving 3248 citations. Previous affiliations of Hirokazu Murakami include RMIT University.
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Journal ArticleDOI
Immunomodulation by vitamin B12: augmentation of CD8+ T lymphocytes and natural killer (NK) cell activity in vitamin B12-deficient patients by methyl-B12 treatment.
J Tamura,Kazuo Kubota,Hirokazu Murakami,Morio Sawamura,T Matsushima,T Tamura,Takayuki Saitoh,H Kurabayshi,Takuji Naruse +8 more
TL;DR: It is concluded that vit.B12 acts as an immunomodulator for cellular immunity, especially relativing to CD8+ cells and the NK cell system, which suggests effects on cytotoxic cells.
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The usefulness of (18)F-fluorodeoxyglucose positron emission tomography ((18)F-FDG-PET) and a comparison of (18)F-FDG-pet with (67)gallium scintigraphy in the evaluation of lymphoma: relation to histologic subtypes based on the World Health Organization classification.
Norifumi Tsukamoto,Masaru Kojima,Masatoshi Hasegawa,Noboru Oriuchi,Takafumi Matsushima,Akihiko Yokohama,Takayuki Saitoh,Hiroshi Handa,Keigo Endo,Hirokazu Murakami +9 more
TL;DR: (18)F-FDG-PET was useful for all histologic subtypes of lymphoma other than SLL and SMZL and the sensitivity of (67)Ga was unexpectedly poor for FL, for mantle cell lymphoma (MCL), and for the nasal type of natural killer/T-cell lymphomas (NK/t-nasal), ranging from 30% to 38%.
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Induction therapy by frequent administration of doxorubicin with four other drugs, followed by intensive consolidation and maintenance therapy for adult acute lymphoblastic leukemia: the JALSG-ALL93 study.
Jin Takeuchi,Taiichi Kyo,Kensuke Naito,H Sao,Masatomo Takahashi,S Miyawaki,Kazutaka Kuriyama,Shigeki Ohtake,Fumiharu Yagasaki,Hirokazu Murakami,Norio Asou,Ino T,Takahiro Okamoto,Noriko Usui,Miki Nishimura,Katsuji Shinagawa,T Fukushima,Hirokuni Taguchi,Takeshi Morii,Shuichi Mizuta,Hideki Akiyama,Y Nakamura,Ohshima T,Ryuzo Ohno +23 more
TL;DR: In order to improve the disappointing prognosis of adult patients with acute lymphoblastic leukemia, similar induction therapy as that used for acute myeloid leukemia (AML), ie frequent administration of doxorubicin (DOX), was applied, and Ph-negative chromosome was a common favorable prognostic factor for CR, longer OS and DFS.
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High Th1/Th2 ratio in patients with chronic idiopathic thrombocytopenic purpura
Hatsue Ogawara,Hiroshi Handa,Kimio Morita,Masaki Hayakawa,Junko Kojima,Hatsuo Amagai,Yuki Tsumita,Yoriaki Kaneko,Norifumi Tsukamoto,Yoshihisa Nojima,Hirokazu Murakami +10 more
TL;DR: The high Th1/Th2 ratio was closely related to the etiology and disease status of chronic ITP.
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Differential ability of polymorphic OGG1 proteins to suppress mutagenesis induced by 8-hydroxyguanine in human cell in vivo.
Arito Yamane,Takashi Kohno,Kohei Ito,Noriaki Sunaga,Kazunori Aoki,Kimio Yoshimura,Hirokazu Murakami,Yoshihisa Nojima,Jun Yokota +8 more
TL;DR: The results indicated that O GG1-Cys326 has a lower ability to prevent mutagenesis by 8OHG than OGG1-Ser326 in vivo in human cells; supporting the results of recent association studies that OGG 1- Cys326 is a risk allele for several types of human cancers.