A
Arito Yamane
Researcher at Gunma University
Publications - 53
Citations - 5064
Arito Yamane is an academic researcher from Gunma University. The author has contributed to research in topics: Cytidine deaminase & Chromatin. The author has an hindex of 24, co-authored 53 publications receiving 4576 citations. Previous affiliations of Arito Yamane include National Institutes of Health & National Cancer Research Institute.
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Journal ArticleDOI
c-Myc Is a Universal Amplifier of Expressed Genes in Lymphocytes and Embryonic Stem Cells
Zuqin Nie,Gangqing Hu,Gang Wei,Kairong Cui,Arito Yamane,Wolfgang Resch,Ruoning Wang,Douglas R. Green,Lino Tessarollo,Rafael Casellas,Keji Zhao,David Levens +11 more
TL;DR: To observe Myc target expression and function in a system where Myc is temporally and physiologically regulated, the transcriptomes and the genome-wide distributions of Myc, RNA polymerase II, and chromatin modifications were compared during lymphocyte activation and in ES cells as well.
Journal ArticleDOI
Rif1 Prevents Resection of DNA Breaks and Promotes Immunoglobulin Class Switching
Michela Di Virgilio,Elsa Callen,Arito Yamane,Wenzhu Zhang,Mila Jankovic,Alexander D. Gitlin,Niklas Feldhahn,Wolfgang Resch,Thiago Y. Oliveira,Thiago Y. Oliveira,Thiago Y. Oliveira,Brian T. Chait,André Nussenzweig,Rafael Casellas,Davide F. Robbiani,Michel C. Nussenzweig,Michel C. Nussenzweig +16 more
TL;DR: Rap1-interacting factor 1 (Rif1) is identified as an ATM (ataxia-telangiectasia mutated) phosphorylation-dependent interactor of 53BP1 and it is shown that absence of Rif1 results in 5′-3′ DNA-end resection in mice.
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Activation-Induced Cytidine Deaminase Targets DNA at Sites of RNA Polymerase II Stalling by Interaction with Spt5
Rushad Pavri,Anna Gazumyan,Anna Gazumyan,Mila Jankovic,Michela Di Virgilio,Isaac A. Klein,Camilo Ansarah-Sobrinho,Wolfgang Resch,Arito Yamane,Bernardo Reina San-Martin,Bernardo Reina San-Martin,Vasco M. Barreto,Vasco M. Barreto,Thomas J.F. Nieland,David E. Root,Rafael Casellas,Michel C. Nussenzweig,Michel C. Nussenzweig +17 more
TL;DR: An shRNA screen to identify factors required for class switch recombination (CSR) of antibody loci found that Spt5, a factor associated with stalled RNA polymerase II (Pol II) and single stranded DNA (ssDNA), is required for CSR.
Journal ArticleDOI
Regulation of MicroRNA Expression and Abundance during Lymphopoiesis
Stefan Kuchen,Wolfgang Resch,Arito Yamane,Nan Kuo,Zhiyu Li,Tirtha Chakraborty,Lai Wei,Arian Laurence,Tomoharu Yasuda,Siying Peng,Jane Hu-Li,Kristina T. Lu,Wendy Dubois,Yoshiaki Kitamura,Nicolas Charles,Hong-Wei Sun,Stefan A. Muljo,Pamela L. Schwartzberg,William E. Paul,John J. O'Shea,Klaus Rajewsky,Rafael Casellas +21 more
TL;DR: This work shows that lymphocyte-specific miRNAs are either tightly controlled by polycomb group-mediated H3K27me3 or maintained in a semi-activated epigenetic state prior to full expression.
Journal ArticleDOI
Translocation-capture sequencing reveals the extent and nature of chromosomal rearrangements in B lymphocytes.
Isaac A. Klein,Wolfgang Resch,Mila Jankovic,Thiago Y. Oliveira,Thiago Y. Oliveira,Arito Yamane,Hirotaka Nakahashi,Michela Di Virgilio,Anne Bothmer,André Nussenzweig,Davide F. Robbiani,Rafael Casellas,Michel C. Nussenzweig,Michel C. Nussenzweig +13 more
TL;DR: Translocation Capture Sequencing (TC-Seq) as mentioned in this paper is a method to document chromosomal rearrangements genome-wide, in primary cells in B cell lymphoma, revealing that proximity between DSBs, transcriptional activity and chromosome territories are key determinants of genome rearrangement.