H
Hiromitsu Kishimoto
Researcher at Indiana University
Publications - 16
Citations - 1785
Hiromitsu Kishimoto is an academic researcher from Indiana University. The author has contributed to research in topics: Medicine & Internal medicine. The author has an hindex of 4, co-authored 4 publications receiving 1665 citations.
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Journal ArticleDOI
CD44 + /CD24 - breast cancer cells exhibit enhanced invasive properties: an early step necessary for metastasis
Carol Sheridan,Hiromitsu Kishimoto,Robyn K. Fuchs,Sanjana Mehrotra,Poornima Bhat-Nakshatri,Charles H. Turner,Robert J. Goulet,Sunil Badve,Harikrishna Nakshatri +8 more
TL;DR: Breast cancer cells with CD44+/CD24- subpopulation express higher levels of proinvasive genes and have highly invasive properties, however, this phenotype is not sufficient to predict capacity for pulmonary metastasis.
Journal ArticleDOI
NF-κ B Promotes Breast Cancer Cell Migration and Metastasis by Inducing the Expression of the Chemokine Receptor CXCR4
Gregory M. Helbig,Kent W. Christopherson,Poornima Bhat-Nakshatri,Suresh M. Kumar,Hiromitsu Kishimoto,Kathy D. Miller,Hal E. Broxmeyer,Harikrishna Nakshatri +7 more
TL;DR: It is demonstrated that NF-κB regulates the motility of breast cancer cells by directly up-regulating the expression of CXCR4 and the SDF-1α-mediated migration is observed with cancer cells that metastasized to the lungs.
Journal ArticleDOI
Interleukin-1α promotes tumor growth and cachexia in MCF-7 xenograft model of breast cancer
Suresh M. Kumar,Hiromitsu Kishimoto,Hui Lin Chua,Sunil Badve,Kathy D. Miller,Robert M. Bigsby,Harikrishna Nakshatri +6 more
TL;DR: It is suggested that cancer cell-derived cytokines, such as IL-1α, induce cachexia by affecting leptin-dependent metabolic pathways by affecting tumor-derived leptin.
Journal ArticleDOI
The p160 family coactivators regulate breast cancer cell proliferation and invasion through autocrine/paracrine activity of SDF-1α/CXCL12
Hiromitsu Kishimoto,Zhuo Wang,Poornima Bhat-Nakshatri,David Chang,Robert Clarke,Harikrishna Nakshatri +5 more
TL;DR: The results suggest that coactivators control SDF-1alpha expression, which mediates estrogen-induced proliferation and invasion through autocrine and paracrine mechanisms, respectively.
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COVID-19 transmission in dental and oral/maxillofacial surgical practice during pandemic: questionnaire survey in 51 university hospitals in Japan
H. Tanaka,Hiroshi Kurita,Yasuyuki Shibuya,Daichi Chikazu,Mituyoshi Iino,K. Hoshi,W. Kobayashi,Satoshi Yokoo,Kanae Kawano,Kenji Mitsudo,Akiyoshi Miyazaki,Yasuto Ota,Hiromitsu Kishimoto,Yoshiyuki Mori,T. Yamamoto +14 more
TL;DR: In this paper , the authors investigated whether dental and oral/maxillofacial procedures are associated with the occurrence of COVID-19 clusters and measures taken to prevent nosocomial infection in dental clinics.