H
Hiroto Hatabu
Researcher at Brigham and Women's Hospital
Publications - 432
Citations - 20053
Hiroto Hatabu is an academic researcher from Brigham and Women's Hospital. The author has contributed to research in topics: Lung cancer & Lung. The author has an hindex of 69, co-authored 398 publications receiving 16544 citations. Previous affiliations of Hiroto Hatabu include University of Pennsylvania & Beth Israel Deaconess Medical Center.
Papers
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Journal ArticleDOI
Monitoring immune-checkpoint blockade: response evaluation and biomarker development
TL;DR: The biological mechanisms underlying the unconventional response patterns associated withICB are reviewed, strategies for the objective assessments of such responses are described, and ongoing efforts to identify biomarkers are highlighted, in order to guide treatment with ICB.
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Incidence of Programmed Cell Death 1 Inhibitor–Related Pneumonitis in Patients With Advanced Cancer: A Systematic Review and Meta-analysis
TL;DR: The incidence of PD-1 inhibitor-related pneumonitis was higher in NSCLC and RCC and during combination therapy and these findings contribute to awareness among clinicians to meet the clinical needs.
Journal ArticleDOI
Lung Volumes and Emphysema in Smokers with Interstitial Lung Abnormalities
George R. Washko,Gary M. Hunninghake,Isis E. Fernandez,Mizuki Nishino,Yuka Okajima,Tsuneo Yamashiro,James C. Ross,Raúl San José Estépar,David A. Lynch,John Brehm,Katherine P. Andriole,Alejandro A. Diaz,Ramin Khorasani,Katherine D'Aco,Frank C. Sciurba,Edwin K. Silverman,Hiroto Hatabu,Ivan O. Rosas +17 more
TL;DR: In smokers, interstitial lung abnormalities were associated with reduced total lung capacity and a lesser amount of emphysema and were positively associated with both greater exposure to tobacco smoke and current smoking.
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Noninvasive assessment of regional ventilation in the human lung using oxygen-enhanced magnetic resonance imaging.
Robert R. Edelman,Hiroto Hatabu,Hiroto Hatabu,Eiji Tadamura,Eiji Tadamura,Wei Li,Wei Li,Potthumarthi V. Prasad,Potthumarthi V. Prasad +8 more
TL;DR: A novel approach for ventilation scanning is proposed, using magnetic resonance imaging (MRI) and inhaled molecular oxygen as a contrast agent, that directly depicts transfer of oxygen across the alveolus into the pulmonary vasculature.
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PD-1 Inhibitor–Related Pneumonitis in Advanced Cancer Patients: Radiographic Patterns and Clinical Course
Mizuki Nishino,Nikhil H. Ramaiya,Mark M. Awad,Lynette M. Sholl,Jennifer A. Maattala,Myriam Taibi,Hiroto Hatabu,Patrick A. Ott,Philippe Armand,F. Stephen Hodi +9 more
TL;DR: PD-1 inhibitor–related pneum onitis showed a spectrum of radiographic patterns, reflecting pneumonitis grades, and was the most common pattern across tumor types and therapeutic regimens.