F
Frank C. Sciurba
Researcher at University of Pittsburgh
Publications - 383
Citations - 28466
Frank C. Sciurba is an academic researcher from University of Pittsburgh. The author has contributed to research in topics: COPD & Medicine. The author has an hindex of 76, co-authored 337 publications receiving 24719 citations. Previous affiliations of Frank C. Sciurba include Boston University & Johns Hopkins University School of Medicine.
Papers
More filters
Journal ArticleDOI
The Nature of Small-Airway Obstruction in Chronic Obstructive Pulmonary Disease
James C. Hogg,Fanny Chu,Soraya Utokaparch,Ryan Woods,W. Mark Elliott,Liliana Buzatu,Ruben M. Cherniack,Robert M. Rogers,Frank C. Sciurba,Harvey O. Coxson,Peter D. Paré +10 more
TL;DR: Progression of COPD is associated with the accumulation of inflammatory mucous exudates in the lumen and infiltration of the wall by innate and adaptive inflammatory immune cells that form lymphoid follicles, coupled to a repair or remodeling process that thickens the walls of these airways.
Journal ArticleDOI
An official European Respiratory Society/American Thoracic Society Technical Standard: field walking tests in chronic respiratory disease
Anne E Holland,Martijn A. Spruit,Thierry Troosters,Milo A. Puhan,Véronique Pepin,Didier Saey,Meredith C. McCormack,Brian W. Carlin,Frank C. Sciurba,Fabio Pitta,J. Wanger,Neil R. MacIntyre,David A. Kaminsky,Bruce H. Culver,S M Revill,Nidia A. Hernandes,Vasileios Andrianopoulos,Carlos Augusto Camillo,Katy E. Mitchell,Annemarie L. Lee,Catherine J. Hill,Sally J Singh +21 more
TL;DR: The aim of this document is to describe the standard operating procedures for the 6MWT, ISWT and ESWT, which can be consistently employed by clinicians and researchers, and reflect current evidence regarding procedures that should be used to achieve robust results.
Journal ArticleDOI
Azithromycin for Prevention of Exacerbations of COPD
Richard K. Albert,Richard K. Albert,John E. Connett,William C. Bailey,Richard Casaburi,J. Allen D. Cooper,Gerard J. Criner,Jeffrey L. Curtis,Mark T. Dransfield,MeiLan K. Han,Stephen C. Lazarus,Barry J. Make,Nathaniel Marchetti,Fernando J. Martinez,Nancy E. Madinger,Charlene McEvoy,Dennis E. Niewoehner,Janos Porsasz,Connie S. Price,Connie S. Price,John J. Reilly,Paul D. Scanlon,Frank C. Sciurba,Steven M. Scharf,George R. Washko,Prescott G. Woodruff,Nicholas R. Anthonisen +26 more
TL;DR: Among selected subjects with COPD, azithromycin taken daily for 1 year, when added to usual treatment, decreased the frequency of exacerbations and improved quality of life but caused hearing decrements in a small percentage of subjects.
Journal ArticleDOI
Chronic obstructive pulmonary disease phenotypes: the future of COPD.
MeiLan K. Han,Alvar Agusti,Peter M.A. Calverley,Bartolome R. Celli,Gerard J. Criner,Jeffrey L. Curtis,Leonardo M. Fabbri,Jonathan G. Goldin,Paul W. Jones,William MacNee,Barry J. Make,Klaus F. Rabe,Stephen I. Rennard,Frank C. Sciurba,Edwin K. Silverman,Jørgen Vestbo,George R. Washko,Emiel F.M. Wouters,Fernando J. Martinez +18 more
TL;DR: This work proposes the following variation on this definition of COPD phenotypes: "a single or combination of disease attributes that describe differences between individuals with COPD as they relate to clinically meaningful outcomes (symptoms, exacerbations, response to therapy, rate of disease progression, or death)."
Journal ArticleDOI
A randomized study of endobronchial valves for advanced emphysema.
Frank C. Sciurba,Armin Ernst,Felix J.F. Herth,Charlie Strange,Gerard J. Criner,Charles H. Marquette,Kevin L. Kovitz,Richard P. Chiacchierini,Jonathan G. Goldin,Geoffrey McLennan +9 more
TL;DR: Endobronchial-valve treatment for advanced heterogeneous emphysema induced modest improvements in lung function, exercise tolerance, and symptoms at the cost of more frequent exacerbations of COPD, pneumonia, and hemoptysis after implantation.