H
Hiroyuki Fuchino
Researcher at Osaka University
Publications - 93
Citations - 1288
Hiroyuki Fuchino is an academic researcher from Osaka University. The author has contributed to research in topics: Chemistry & Medicine. The author has an hindex of 19, co-authored 82 publications receiving 1023 citations. Previous affiliations of Hiroyuki Fuchino include Tokushima Bunri University.
Papers
More filters
Journal ArticleDOI
Anti-hepatitis C virus compounds obtained from Glycyrrhiza uralensis and other Glycyrrhiza species.
Myrna Adianti,Chie Aoki,Mari Komoto,Lin Deng,Ikuo Shoji,Tutik Sri Wahyuni,Maria Inge Lusida,Soetjipto,Hiroyuki Fuchino,Nobuo Kawahara,Hak Hotta +10 more
TL;DR: The present results suggest that glycycoumarin, glycyrin, Glycyrol and liquiritigenin isolated from G. uralensis, as well as isoliquiritigin, licochalcone A and glabridin, would be good candidates for seed compounds to develop antivirals against HCV.
Journal ArticleDOI
Pterosin B prevents chondrocyte hypertrophy and osteoarthritis in mice by inhibiting Sik3
Yasuhito Yahara,Hiroshi Takemori,Minoru Okada,Azuma Kosai,Akihiro Yamashita,Tomohito Kobayashi,Kaori Fujita,Yumi Itoh,Masahiro Nakamura,Hiroyuki Fuchino,Nobuo Kawahara,Naoshi Fukui,Akira Watanabe,Tomoatsu Kimura,Noriyuki Tsumaki +14 more
TL;DR: It is suggested that chondrocyte-specific salt-inducible kinase 3 regulates the homeostasis of articular cartilage and is a target for the treatment of osteoarthritis, with pterosin B as a candidate therapeutic.
Journal ArticleDOI
In vitro screening of leishmanicidal activity in myanmar timber extracts.
TL;DR: From a literature search for reports on the chemical constituents of these plants, most constituents were found to be quinone derivatives or other compounds with unsaturated carbonyl groups.
Journal ArticleDOI
Decoralin, a novel linear cationic α-helical peptide from the venom of the solitary eumenine wasp Oreumenes decoratus
Katsuhiro Konno,Marisa Rangel,Joacir Stolarz Oliveira,Marcia Perez dos Santos Cabrera,Renato Fontana,Izaura Y. Hirata,Izumi Hide,Yoshihiro Nakata,Kanami Mori,Marii Kawano,Hiroyuki Fuchino,Setsuko Sekita,João Ruggiero Neto +12 more
TL;DR: A novel peptide, decoralin, was isolated from the venom of the solitary eumenine wasp Oreumenes decoratus and exhibited a significant broad-spectrum antimicrobial activity, and moderate mast cell degranulation and leishmanicidal activities, but showed virtually no hemolytic activity.
Journal ArticleDOI
In vitro leishmanicidal activity of some scarce natural products
TL;DR: Leishmanicidal activity of 46 natural products including several fern and Betula constituents was examined, and it was found that the carbonyl group at C‐11 is necessary for the activity of biphenyl‐types.