H
Hitoshi Arita
Researcher at Osaka University
Publications - 124
Citations - 6119
Hitoshi Arita is an academic researcher from Osaka University. The author has contributed to research in topics: Receptor & Phospholipase A2. The author has an hindex of 40, co-authored 124 publications receiving 5985 citations. Previous affiliations of Hitoshi Arita include Kyushu University.
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Journal ArticleDOI
Identification of the Product of Growth Arrest-specific Gene 6 as a Common Ligand for Axl, Sky, and Mer Receptor Tyrosine Kinases
Kyoko Nagata,Kazumasa Ohashi,Toru Nakano,Hitoshi Arita,Chen Zong,Hidesaburo Hanafusa,Kensaku Mizuno +6 more
TL;DR: Findings suggest that Gas6 is a common ligand for Axl, Sky, and Mer, all known members of an Axl/Sky receptor subfamily.
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Inflammatory factors stimulate expression of group ii phospholipase a2 in rat cultured astrocytes : two distinct pathways of the gene expression
Shogo Oka,Hitoshi Arita +1 more
TL;DR: The results suggest that PLA2-II in the brain plays important roles in the inflammatory response, and conclude that the TNF-activated pathway differs from the LPS-activated one: the former is enhanced by cAMP and the latter involves protein kinase C.
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Cell adhesion to phosphatidylserine mediated by a product of growth arrest-specific gene 6.
Toru Nakano,Yoshikazu Ishimoto,Junji Kishino,Masato Umeda,Keizo Inoue,Kyoko Nagata,Kazumasa Ohashi,Kensaku Mizuno,Hitoshi Arita +8 more
TL;DR: Findings suggest that Gas6 may play a role in recognition of cells exposing phosphatidylserine on their surfaces by phagocytic cells, which is supposed to be one of the mechanisms for clearing dying cells.
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Glucocorticoids suppress group II phospholipase A2 production by blocking mRNA synthesis and post-transcriptional expression.
TL;DR: The data suggest that the mechanism mediating forskolin-induced mRNA accumulation is sensitive to glucocorticoids, but the mechanismmediating the TNF-induced accumulation is not, and inhibition of T NF-induced PLA2 release by glucocorts may be explained by the blocking of post-transcriptional synthesis of the group II PLA2.
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Vascular Smooth Muscle Cell-derived, Gla-containing Growth-potentiating Factor for Ca2+-mobilizing Growth Factors (∗)
Toru Nakano,Ken-ichi Higashino,Norihisa Kikuchi,Junji Kishino,Koji Nomura,Hiroko Fujita,Osamu Ohara,Hitoshi Arita +7 more
TL;DR: GPF specifically potentiated cell proliferation mediated by Ca-mobilizing receptors, suggesting that GPF may be a new type of extracellular factor regulating VSMC proliferation.