Ho Jin Kim

TL;DR: This study confirms that effector cytokine production by normal human B cells is context dependent and demonstrates that this involves the reciprocal regulation of proinflammatory and anti-inflammatory cytokines, and proposes a model that ascribes distinct and proactive roles to memory and naive B cell subsets in the regulation of memory immune responses and in autoimmunity.

TL;DR: In this article, the authors proposed indications for MOG-IgG testing based on expert consensus, and gave a list of conditions atypical for MG-EM (red flags) that should prompt physicians to challenge a positive MOG IgG test result, and provided recommendations regarding assay methodology, specimen sampling and data interpretation.

TL;DR: MRI findings of neuromyelitis optica and its spectrum disorder (NMOSD) are reviewed, finding brain, optic nerve, and spinal cord MRI findings of NMOSD to be of increased interest.

TL;DR: Patients with AQP4-IgG-positive NMOSD who received eculizumab had a significantly lower risk of relapse than those who received placebo, and there was no significant between-group difference in measures of disability progression.

TL;DR: Compared with placebo, inebilizumab reduced the risk of an NMOSD attack and has potential application as an evidence-based treatment for patients withNMOSD.