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Hong-Yu Zhang

Researcher at Huazhong Agricultural University

Publications -  254
Citations -  7792

Hong-Yu Zhang is an academic researcher from Huazhong Agricultural University. The author has contributed to research in topics: Density functional theory & Gene. The author has an hindex of 41, co-authored 245 publications receiving 6877 citations. Previous affiliations of Hong-Yu Zhang include Shandong Normal University & Shandong University of Technology.

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Natural products and drug discovery. Can thousands of years of ancient medical knowledge lead us to new and powerful drug combinations in the fight against cancer and dementia

TL;DR: Many antibiotics are used commercially, or are potentially useful in medicine for purposes other than their antimicrobial action, and are used as antitumor agents, enzyme inhibitors including powerful hypocholesterolemic agents, immunosuppressive agents, antimigraine agents, and so on.
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Estimation of Scavenging Activity of Phenolic Compounds Using the ABTS^·^+ Assay

TL;DR: It can be argued that the ABTS(*+) assay may give an indication for the presence of antioxidants in a certain system but SARs cannot be readily inferred.
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Substituent effects on O--H bond dissociation enthalpies and ionization potentials of catechols: a DFT study and its implications in the rational design of phenolic antioxidants and elucidation of structure-activity relationships for flavonoid antioxidants.

TL;DR: It was revealed that the ortho hydroxyl of catechol was effective for the reduction of the O--H BDE; however, the group had little influence on the IP; and 1,4-pyrone was unlikely to be favorable to enhance the H-abstraction activity of flavonoids.
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Evaluation of a new copper(II)-curcumin complex as superoxide dismutase mimic and its free radical reactions.

TL;DR: It is confirmed that the new Cu(II)-curcumin complex possesses SOD activity, free radical neutralizing ability, and antioxidant potential, and quantum chemical calculations with density functional theory have been performed to support the experimental observations.