H
Hope T. Beier
Researcher at Air Force Research Laboratory
Publications - 84
Citations - 1686
Hope T. Beier is an academic researcher from Air Force Research Laboratory. The author has contributed to research in topics: Raman spectroscopy & Membrane. The author has an hindex of 23, co-authored 84 publications receiving 1532 citations. Previous affiliations of Hope T. Beier include Texas A&M University & Texas A&M University System.
Papers
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Journal ArticleDOI
Nanofluidic biosensing for beta-amyloid detection using surface enhanced Raman spectroscopy.
I-Hsien Chou,Melodie Benford,Hope T. Beier,Gerard L. Coté,Miao Wang,Nan Jing,Jun Kameoka,Theresa A. Good +7 more
TL;DR: A novel nanofluidic biosensor using a controlled, reproducible surface enhanced Raman spectroscopy active site was developed to observe Abeta in different conformational states during the Abeta self-assembly process as well as to distinguish Abeta from confounder proteins commonly found in cerebral spinal fluid.
Journal ArticleDOI
Bipolar nanosecond electric pulses are less efficient at electropermeabilization and killing cells than monopolar pulses.
Bennett L. Ibey,Jody C. Ullery,Olga N. Pakhomova,Caleb C. Roth,Iurii Semenov,Hope T. Beier,Melissa Tarango,Shu Xiao,Karl H. Schoenbach,Andrei G. Pakhomov +9 more
TL;DR: Overall, unlike longer pulse exposures, BP nanosecond-pulsed electric fields (nsPEF) exposures proved far less effective at both membrane permeabilization and cell killing than MP nsPEF.
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Cancellation of cellular responses to nanoelectroporation by reversing the stimulus polarity
Andrei G. Pakhomov,Iurii Semenov,Shu Xiao,Olga N. Pakhomova,Betsy Gregory,Karl H. Schoenbach,Jody C. Ullery,Hope T. Beier,Sambasiva R. Rajulapati,Bennett L. Ibey +9 more
TL;DR: A novel phenomenon of bioeffects cancellation is reported that puts nsEP cardinally apart from the conventional electroporation and electrostimulation by milli- and microsecond pulses, and provides new insights into effects of more complex waveforms, including pulsed electromagnetic emissions.
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Bright emission from a random Raman laser
Brett H. Hokr,Joel N. Bixler,Michael T. Cone,John D. Mason,Hope T. Beier,Gary D. Noojin,Georgi I. Petrov,Leonid A. Golovan,Robert J. Thomas,Benjamin A. Rockwell,Vladislav V. Yakovlev +10 more
TL;DR: This work demonstrates the first experimental evidence of lasing via a Raman interaction in a bulk three-dimensional random medium, with conversion efficiencies on the order of a few percent.
Journal ArticleDOI
Application of Surface-Enhanced Raman Spectroscopy for Detection of Beta Amyloid Using Nanoshells
Hope T. Beier,Christopher B. Cowan,I-Hsien Chou,James Pallikal,James E. Henry,James E. Henry,Melodie Benford,Joseph B. Jackson,Theresa A. Good,Gerard L. Coté +9 more
TL;DR: In this article, a nanoshell substrate, functionalized with sialic acid residues to mimic neuron cell surfaces, was developed for the surface-enhanced Raman detection of β-amyloid.