H
Howard Alper
Researcher at University of Ottawa
Publications - 162
Citations - 4578
Howard Alper is an academic researcher from University of Ottawa. The author has contributed to research in topics: Catalysis & Palladium. The author has an hindex of 38, co-authored 162 publications receiving 4161 citations. Previous affiliations of Howard Alper include Carleton College.
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Journal ArticleDOI
Redox‐Neutral α‐Allylation of Amines by Combining Palladium Catalysis and Visible‐Light Photoredox Catalysis
Jun Xuan,Ting-Ting Zeng,Zhu-Jia Feng,Qiao-Hui Deng,Jia-Rong Chen,Liang-Qiu Lu,Wen-Jing Xiao,Wen-Jing Xiao,Howard Alper +8 more
TL;DR: An unprecedented α-allylation of amines was achieved by combining palladiumCatalysis and visible-light photoredox catalysis and the transformation was applied to the formal synthesis of 8-oxoprotoberberine derivatives which show potential anticancer properties.
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Magnetic nanoparticle-supported proline as a recyclable and recoverable ligand for the CuI catalyzed arylation of nitrogen nucleophiles
TL;DR: This magnetic nanoparticle-supported proline ligand was prepared and used for the CuI catalyzed Ullmann-type coupling reactions of aryl/heteroaryl bromides with various nitrogen heterocycles to form the corresponding N-aryl products in good to excellent yields.
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Highly efficient, recyclable Pd(II) catalysts with bisimidazole ligands for the Heck reaction in ionic liquids.
Soon Bong Park,Howard Alper +1 more
TL;DR: New Pd(II) complexes with bisimidazole ligands were prepared and proved to be effective catalysts for the Heck reaction under phosphine-free conditions using ionic liquids as solvents.
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Palladium-catalyzed cyclocarbonylation of o-iodoanilines with heterocumulenes: regioselective preparation of 4(3H)-quinazolinone derivatives
Chitchamai Larksarp,Howard Alper +1 more
TL;DR: Urea-type intermediates are believed to be generated first in situ from the reaction of o-iodoanilines with heterocumulenes, followed by palladium-catalyzed carbonylation and cyclization to yield the products.
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An efficient synthesis of propargylamines via C-H activation catalyzed by copper(I) in ionic liquids.
Soon Bong Park,Howard Alper +1 more
TL;DR: A readily available copper(I) catalyst, in an ionic liquid, can effect three-component coupling of aldehydes, amines and alkynes to generate propargylamines in high yields.