H
Howard Zhang
Researcher at University of Maryland, Baltimore
Publications - 6
Citations - 1078
Howard Zhang is an academic researcher from University of Maryland, Baltimore. The author has contributed to research in topics: Lung cancer & Sputum. The author has an hindex of 6, co-authored 6 publications receiving 1012 citations.
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Journal ArticleDOI
Plasma microRNAs as potential biomarkers for non-small-cell lung cancer
Jun Shen,Nevins W. Todd,Howard Zhang,Lei Yu,Xing Lingxiao,Xing Lingxiao,Yuping Mei,Maria A. Guarnera,Jipei Liao,Amy Chou,Changwan Larry Lu,Zhengran Jiang,Hong-Bin Fang,Ruth L. Katz,Feng Jiang +14 more
TL;DR: Altered expressions of the miRNAs in plasma would provide potential blood-based biomarkers for NSCLC.
Journal ArticleDOI
Early detection of lung adenocarcinoma in sputum by a panel of microRNA markers
Lei Yu,Nevins W. Todd,Lingxiao Xing,Ying Xie,Howard Zhang,Zhenqiu Liu,Hong-Bin Fang,Jian Zhang,Ruth L. Katz,Feng Jiang +9 more
TL;DR: A panel of miRNAs that can be used as highly sensitive and specific sputum markers for early detection of lung adenocarcinoma were developed and demonstrated the potential of translation to laboratory settings for improving the early detection.
Journal ArticleDOI
Diagnosis of lung cancer in individuals with solitary pulmonary nodules by plasma microRNA biomarkers
Jun Shen,Ziling Liu,Nevins W. Todd,Howard Zhang,Jipei Liao,Lei Yu,Maria A. Guarnera,Ruiyun Li,Ling Cai,Min Zhan,Feng Jiang +10 more
TL;DR: The plasma miRNAs provide potential circulating biomarkers for noninvasively diagnosing lung cancer among individuals with SPNs, and could be further evaluated in clinical trials.
Journal ArticleDOI
Sputum microRNA biomarkers for identifying lung cancer in indeterminate solitary pulmonary nodules.
Lingxiao Xing,Jian Su,Maria A. Guarnera,Howard Zhang,Ling Cai,Rixin Zhou,Sanford A. Stass,Feng Jiang +7 more
TL;DR: Sputum miRNA biomarkers may improve LDCT screening for lung cancer in heavy smokers by preoperatively diagnosing malignant SPNs by proving sensitivity and specificity and a prospective study in a large population is needed.
Journal ArticleDOI
A panel of sputum-based genomic marker for early detection of lung cancer.
TL;DR: A gene panel could provide sputum-based markers that have the potential to improve early detection of lung SCCs, and had higher sensitivity and specificity in identification of squamous cell carcinoma than in adenocarcinoma of the lungs.