H
Hua Zhong
Researcher at University of Texas Southwestern Medical Center
Publications - 8
Citations - 112
Hua Zhong is an academic researcher from University of Texas Southwestern Medical Center. The author has contributed to research in topics: Cancer & Eosinophilic. The author has an hindex of 4, co-authored 8 publications receiving 36 citations. Previous affiliations of Hua Zhong include New Mexico State University.
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Journal ArticleDOI
Efficient weighted univariate clustering maps outstanding dysregulated genomic zones in human cancers.
Mingzhou Song,Hua Zhong +1 more
TL;DR: Efficient chromosome clustering opens a window to characterize molecular patterns in cancer genome and beyond, and identifies strong continuity in dysregulation polarity—dominance by either up- or downregulated genes in a zone—along chromosomes in all cancer types.
Journal ArticleDOI
Germline and sporadic mTOR pathway mutations in low-grade oncocytic tumor of the kidney.
Payal Kapur,Payal Kapur,Joanna Zawiejska-Rataj,Ming Gao,Hua Zhong,Suneetha Chintalapati,Midori Mitui,Spencer D. Barnes,Qinbo Zhou,Jeffrey Miyata,Deyssy Carrillo,Venkat S. Malladi,Dinesh Rakheja,Ivan Pedrosa,Lin Xu,Lisa N. Kinch,James Brugarolas +16 more
TL;DR: In this article, the authors describe 22 low-grade oncocytic tumor (LOT) cases corresponding to 7 patients presenting with a median age of 75 years (range 63-86 years) and male to female ratio 2:5.
Journal ArticleDOI
Eosinophilic Vacuolated Tumor of the Kidney: A Review of Evolving Concepts in This Novel Subtype With Additional Insights From a Case With MTOR Mutation and Concomitant Chromosome 1 Loss.
Payal Kapur,Ming Gao,Hua Zhong,Dinesh Rakheja,Qi Cai,Ivan Pedrosa,Vitaly Margulis,Lin Xu,Lisa N. Kinch,James Brugarolas +9 more
TL;DR: In this article, a comprehensive review of the eosinophilic vacuolated tumor (EVT) is presented based upon a case report including radiology, histopathology, electron microscopy, and next-generation sequencing.
Journal ArticleDOI
A Fast Exact Functional Test for Directional Association and Cancer Biology Applications
Hua Zhong,Mingzhou Song +1 more
TL;DR: An exact functional test for directional association by examining the strength of functional dependency is introduced, effective in promoting functional patterns by reducing statistical power on dependent non-functional patterns.
Journal ArticleDOI
A renal cell carcinoma tumorgraft platform to advance precision medicine
Roy Elias,Vanina Tcheuyap,Akash K. Kaushik,Nirmish Singla,Ming Gao,Oscar Reig Torras,Alana Christie,Aditi Mulgaonkar,Layton Woolford,Christina Stevens,Kavitha Priya Kettimuthu,Andrea Pavia-Jimenez,Lindsey K. Boroughs,Allison Joyce,Marianna Dakanali,Hollis Notgrass,Vitaly Margulis,Jeffrey A. Cadeddu,Ivan Pedrosa,Noelle S. Williams,Xiankai Sun,Ralph J. DeBerardinis,Orhan K. Öz,Hua Zhong,Somasekar Seshagiri,Zora Modrusan,Brandi L. Cantarel,Payal Kapur,James Brugarolas +28 more
TL;DR: In this paper, patient-derived tumorgraft (TG) models recapitulate the biology and treatment responsiveness of Renal Cell carcinoma (RCC) through systematic orthotopic implantation of tumor samples from 926 ethnically diverse individuals into non-obese diabetic (NOD)/severe combined immunodeficiency (SCID) mice.