H
Huahao Shen
Researcher at Zhejiang University
Publications - 221
Citations - 7335
Huahao Shen is an academic researcher from Zhejiang University. The author has contributed to research in topics: Inflammation & Asthma. The author has an hindex of 38, co-authored 199 publications receiving 5283 citations. Previous affiliations of Huahao Shen include Guangzhou Medical University.
Papers
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Journal ArticleDOI
YKL-40 expression in chronic obstructive pulmonary disease: relation to acute exacerbations and airway remodeling
Tianwen Lai,Tianwen Lai,Dong Wu,Min Chen,Chao Cao,Zhiliang Jing,Li Huang,Yingying Lv,Xuanna Zhao,Quanchao Lv,Yajun Wang,Dongming Li,Bin Wu,Huahao Shen +13 more
TL;DR: YKL-40 expression is up-regulated in patients with COPD and correlates with exacerbation attacks and may contribute to airway remodeling by acting on lung fibroblasts.
Journal ArticleDOI
Activating transcription factor 3 represses cigarette smoke-induced IL6 and IL8 expression via suppressing NF-κB activation.
Yanping Wu,Chao Cao,Yinfang Wu,Miao Li,Tianwen Lai,Chen Zhu,Yong Wang,Songmin Ying,Zhihua Chen,Huahao Shen,Wen Li +10 more
TL;DR: This study shows that ATF3 plays an important role in the negative regulation of CS-induced pro-inflammatory gene expression through downregulating NF-κB phosphorylation.
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The CKLF1-C19 peptide attenuates allergic lung inflammation by inhibiting CCR3- and CCR4-mediated chemotaxis in a mouse model of asthma.
Linjie Tian,Wei Li,Jianli Wang,Yingmei Zhang,Yi Zheng,Hui Qi,Xiaohuan Guo,Defu Ma,Huahao Shen,Yitao Wang +9 more
TL;DR: The CKLF1‐C19 peptide attenuates allergic lung inflammation by inhibiting CCR3‐ and CCR4‐mediated chemotaxis in a mouse model of asthma.
Journal ArticleDOI
Transgelin overexpression in lung adenocarcinoma is associated with tumor progression
TL;DR: TAGLN was upregulated in the human lung adenocarcinoma cell lines under hypoxic conditions, which contributed to the migration ability of the cells, and the data suggest that TAGLN may be a viable therapeutic target and a potential biomarker for predicting the prognosis of patients with lung adentheses.
Journal ArticleDOI
Autophagy inhibitors suppress environmental particulate matter-induced airway inflammation.
Xu-Chen Xu,Yinfang Wu,Jiesen Zhou,Hai-Pin Chen,Yong Wang,Zhou-Yang Li,Yun Zhao,Huahao Shen,Zhi-Hua Chen +8 more
TL;DR: This study shows a paradigm that autophagy inhibitors effectively decrease the PM-induced airway inflammation via suppressing the NF-кB pathway, which may provide novel preventive and/or protective approaches for PM-related airway injury.