H
Huahao Shen
Researcher at Zhejiang University
Publications - 221
Citations - 7335
Huahao Shen is an academic researcher from Zhejiang University. The author has contributed to research in topics: Inflammation & Asthma. The author has an hindex of 38, co-authored 199 publications receiving 5283 citations. Previous affiliations of Huahao Shen include Guangzhou Medical University.
Papers
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Journal ArticleDOI
Clinical and Inflammatory Characteristics of the Chinese APAC Cough Variant Asthma Cohort
Kefang Lai,Wenzhi Zhan,Feng Wu,Yunhui Zhang,Lin Lin,Wen Li,Fang Yi,Ziyu Jiang,Yuanrong Dai,Suyun Li,Jiangtao Lin,Yadong Yuan,Yong Jiang,Chen Qiu,Siming Zhao,Mei-bei Chen,Zhongmin Qiu,Hu Li,Ruchong Chen,Wei Lu,Jiaxing Xie,C. Guo,Mei Jiang,Xiao-Hua Yang,Guochao Shi,Dejun Sun,Rongchang Chen,Kian Fan Chung,Huahao Shen,Nanshan Zhong +29 more
TL;DR: Cough variant asthma is distinctive from classic asthma in regard to clinical features, lung function, and airway inflammation and quality of life is badly impaired as well in spite of better asthma control scores.
Journal ArticleDOI
Human C-C chemokine receptor 3 monoclonal antibody inhibits pulmonary inflammation in allergic mice
TL;DR: The inhibition of airway inflammation and mucus overproduction by the antibody suggested that the blockade of CCR3 is an appealing therapeutical target for asthma.
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Activating Transcription Factor 3 Is Essential for Cigarette Smoke-Induced Mucin Expression via Interaction with Activator Protein-1.
Yanping Wu,Yinfang Wu,Chao Zhang,Hongbin Zhou,Chao Cao,Miao Li,Chen Zhu,Songmin Ying,Zhihua Chen,Huahao Shen,Wen Li +10 more
TL;DR: It is demonstrated that ATF3 may be involved in activator protein-1 signaling and transcriptional promotion of CS-induced MUC5AC expression in airway epithelial cells.
Journal ArticleDOI
Characteristics of different asthma phenotypes associated with cough: a prospective, multicenter survey in China
Jianmeng Zhou,Fang Yi,Feng Wu,P Xu,Mei-bei Chen,Huahao Shen,Ling Lin,Yunhui Zhang,Suyun Li,Chang-Gui Wu,Yadong Yuan,Gang Wang,Xian Ye,Ping Zhang,Huaping Tang,Qianli Ma,Lanqing Huang,Zhongmin Qiu,Haiyan Deng,Chen Qiu,Guochao Shi,Jiayu Pan,Wei Lu,Kian Fan Chung,Nanshan Zhong,Kefang Lai,the Cpa Cohort Study Group +26 more
TL;DR: Wang et al. as mentioned in this paper compared the clinical and pathophysiological characteristics of CPA, CVA, and classic asthma patients to determine any differential phenotypic traits, and found that CPA patients more frequently presented with cough as the initial symptom, and laryngeal symptoms (p < 0.001), had less symptoms related with rhinitis/sinusitis and gastroesophageal reflux, while the proportion of COPD and bronchiectasis was higher in CA patients.
Journal ArticleDOI
Nuclear erythroid 2 p45-related factor-2 Nrf2 ameliorates cigarette smoking-induced mucus overproduction in airway epithelium and mouse lungs.
Yinghua Ying,Xiaoping Lin,Hongbin Zhou,Yinfang Wu,Fugui Yan,Wen Hua,Lixia Xia,Zhangwei Qiu,Zhihua Chen,Wen Li,Huahao Shen +10 more
TL;DR: Nrf2 negatively regulated smoking-induced mucus production in vitro and in vivo, suggesting therapeutic potentials of this factor in airway diseases with hypersecreted mucus.