H
Huahao Shen
Researcher at Zhejiang University
Publications - 221
Citations - 7335
Huahao Shen is an academic researcher from Zhejiang University. The author has contributed to research in topics: Inflammation & Asthma. The author has an hindex of 38, co-authored 199 publications receiving 5283 citations. Previous affiliations of Huahao Shen include Guangzhou Medical University.
Papers
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Journal ArticleDOI
Association between polymorphism of glutathione S-transferase P1 and chronic obstructive pulmonary disease: a meta-analysis.
TL;DR: The GSTP1 105Val/Val genotype is suggested to be a genetic contributor to COPD susceptibility, which should be furthermore clarified by studies with large sample sizes and careful control for age, sex, ethnicity, and cigarette smoking.
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Genomic instability in chronic airway inflammatory diseases.
TL;DR: The roles of DDR in chronic airway inflammatory diseases are highlighted, the possibilities of targeting DDR signaling to develop potential novel treatments against these conditions are discussed, and a better understanding of these diseases is tried.
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Neutrophilic Inflammation in the Immune Responses of Chronic Obstructive Pulmonary Disease: Lessons from Animal Models.
Gang Huang,Xu-Chen Xu,Jiesen Zhou,Zhou-Yang Li,Hai-Pin Chen,Yong Wang,Wen Li,Huahao Shen,Huahao Shen,Zhi-Hua Chen +9 more
TL;DR: A potential new animal model of COPD is proposed, which may mimic the most characteristics of human COPD pathogenesis, including persistent moderate-to-high levels of neutrophilic inflammation.
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Proteomic analysis of sputum reveals novel biomarkers for various presentations of asthma.
Chao Cao,Wen Li,Wen Hua,Fugui Yan,Hao Zhang,Huaqiong Huang,Yinghua Ying,Na Li,Fen Lan,Shaobin Wang,Xiao Chen,Jing Li,J. X. Liu,Tianwen Lai,Zhengqiang Bao,Yuan Cao,Yun Zhao,Gang Huang,Lili Huang,Yaqing Huang,Ping Wu,Chao Peng,Zhihua Chen,Kian Fan Chung,Nanshan Zhong,Songmin Ying,Huahao Shen,Huahao Shen +27 more
TL;DR: Patients with CA, CVA, or CTVA share common clinical characteristics of eosinophilic airway inflammation, and this study identified a pool of novel biomarkers for diagnosis of asthma and to label its subtypes.
Journal ArticleDOI
Scaffolding protein Gab1 regulates myeloid dendritic cell migration in allergic asthma.
Yun Zhang,Yun Xu,Shuwan Liu,Xiaohong Guo,Dong Cen,Jiaqi Xu,Heyuan Li,Kaijun Li,Chunlai Zeng,Linrong Lu,Yi Ting Zhou,Huahao Shen,Hongqiang Cheng,Xue Zhang,Yuehai Ke +14 more
TL;DR: Investigations revealed a prominent reduction in CCL19-mediated migration of Gab1-deficient mDCs to draining lymph nodes and subsequent impairment of Th2-driven adaptive activation, providing the first evidence for the roles ofGab1 in lung, giving deeper understanding of asthmatic pathogenesis.