H
Hub P.J.M. Noteborn
Researcher at Wageningen University and Research Centre
Publications - 16
Citations - 1278
Hub P.J.M. Noteborn is an academic researcher from Wageningen University and Research Centre. The author has contributed to research in topics: Genistein & Substantial equivalence. The author has an hindex of 10, co-authored 16 publications receiving 1242 citations.
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Journal ArticleDOI
Assessment of the food safety issues related to genetically modified foods
TL;DR: The concept of substantial equivalence has been developed as part of a safety evaluation framework, based on the idea that existing foods can serve as a basis for comparing the properties of genetically modified foods with the appropriate counterpart as mentioned in this paper.
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Unintended effects and their detection in genetically modified crops
F. Cellini,A Chesson,Ian J. Colquhoun,Anne Constable,Howard V. Davies,Karl-Heinz Engel,Angharad M. R. Gatehouse,Sirpa Kärenlampi,Esther J. Kok,Jean-Jacques Leguay,Satu Lehesranta,Hub P.J.M. Noteborn,Jan Pedersen,M Smith +13 more
TL;DR: The potential value of evolving "profiling" or "omics" technologies as non-targeted, unbiased approaches, to detect unintended effects in GM crops and products are focused on.
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Chemical fingerprinting for the evaluation of unintended secondary metabolic changes in transgenic food crops.
TL;DR: The utility of an off-line combination of 400 MHz proton (1H)-NMR spectroscopy and liquid chromatography for the multi-component comparison of low-molecular weight compounds (i.e. chemical fingerprinting) in complex plant matrices is examined.
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Substantial equivalence: an appropriate paradigm for the safety assessment of genetically modified foods?
TL;DR: New 'profiling' methods will allow for the screening of potential changes in the modified host organism at different integration levels, i.e. at the genome level, during gene expression and protein translation, and at the level of cellular metabolism.
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Adequacy of methods for testing the safety of genetically modified foods.
TL;DR: Comments by Lachmann, Sykes, and Gosden are disappointing because they reflect a failure to understand the new, and apparently unwelcome, dialogue of accountability that needs to be forged between scientists and the public.