Huey Fang Teh

TL;DR: The quartz crystal microbalance with dissipation monitoring (QCM-D) is introduced as a new alternative to study the conformational differences in protein-DNA complexes and affirm that ligands have remarkable effects on ERalpha- DNA complexes.

TL;DR: In this paper, the authors used surface plasmon resonance spectroscopy (SPR) to study the interactions between human estrogen receptors (ER, alpha and beta subtypes) and estrogen response elements (ERE), with four assay schemes.

TL;DR: Building upon a larger experimentally validated ERE set, the h-ERE algorithm is able to demarcate better the universe of ERE-like sequences that are potential ER binders, and outperformed existing predictive algorithms and produced fewer than 5% false negatives upon experimental validation.

TL;DR: The potential of utilizing SPR and QCM in combination for a comprehensive characterization of ER-DNA interactions, including sequence-dependent binding mechanisms and structural differences in ERalpha-DNA and ERbeta-DNA complexes is demonstrated.

TL;DR: In this article , the reduction of graphene oxide (rGO) utilizing green methods such as plants has attracted much attention due to its productivity, eco-friendly features, and cost effectiveness.