Hui Yu

TL;DR: It is shown that non-coding RNAs perform as well as messenger RNAs in predicting survival of cancer patients, which reinforces the potential prognostic value of non-CodingRNAs.

TL;DR: This study quantitatively analyzed human genome-wide RNA editing events derived from tumor or normal tissues and identified hyper RNA edited genes (protein-coding genes, lincRNAs, and pseudogenes) that embody a large portion of cancer prognostic predictors.

TL;DR: A global expression correlation attenuation within and between key signaling pathways in chronic kidney disease is discovered, with pathway Regulation of nuclear SMAD2/3 signaling demonstrating the most remarkable intra-pathway correlation rewiring.

TL;DR: This work presents the first database that hosts millions of somatic motifs ascribed to a variety of sequence alteration mechanisms, including those for important transcription factors, RNA-binding proteins, miRNA seeds and miRNA–mRNA 3′-UTR target motifs.

TL;DR: This work constructed MutEx, a pan-cancer integrative genomic database that records the relationships among gene expression, somatic mutation and survival data for cancer patients and provides several application examples, including top somatic mutations associated with the most extensive expression dysregulation in breast cancer.