Sergey Ivanov

TL;DR: The studies show an important causal link between hypoxia, extracellular acidification, and induction or enhanced expression of these enzymes in human tumors and conclude that the cell surface transmembrane carbonic anhydrases CA IX and CA XII are overexpressed in many tumors suggesting that this is a common feature of cancer cells that may be required for tumor progression.

TL;DR: To discover genes involved in von Hippel-Lindau (VHL)-mediated carcinogenesis, renal cell carcinoma cell lines stably transfected with wild-type VHL-expressing transgenes were used and large-scale RNA differential display technology applied to identify several differentially expressed genes.

TL;DR: A tectonic interpretation of the breakup and early seafloor spreading between India and Antarctica based on improved coverage of potential field and seismic data off the east Antarctic margin between the Gunnerus Ridge and the Bruce Rise is presented in this article.

TL;DR: Results show that clr4 plays a critical role in silencing at mating-type loci and centromeres through the organization of repressive chromatin structure and demonstrate a new, activator function for Clr4p.

TL;DR: The identification of 16 additional mutations in the coding region of the CCR5 gene, all but 3 of which are codon altering or "nonsynonymous," which is consistent with an adaptive accumulation of function-altering alleles for this gene.