Y
Yu Cheng
Researcher at Shanghai Jiao Tong University
Publications - 15
Citations - 527
Yu Cheng is an academic researcher from Shanghai Jiao Tong University. The author has contributed to research in topics: Amino acid & Metabolite. The author has an hindex of 7, co-authored 15 publications receiving 425 citations. Previous affiliations of Yu Cheng include East China Normal University & Shanghai University.
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Journal ArticleDOI
Distinct urinary metabolic profile of human colorectal cancer.
Yu Cheng,Guoxiang Xie,Tianlu Chen,Yunping Qiu,Xia Zou,Minhua Zheng,Binbin Tan,Bo Feng,Tao-Tao Dong,Pingang He,Linjing Zhao,Aihua Zhao,Lisa X. Xu,Yan Zhang,Wei Jia,Wei Jia +15 more
TL;DR: These findings confirm distinct urinary metabolic footprints of CRC patients characterized by altered levels of metabolites derived from gut microbial-host co-metabolism and provide a novel and promising molecular diagnostic approach for the early detection of CRC.
Journal ArticleDOI
Metabonomics identifies serum metabolite markers of colorectal cancer.
Binbin Tan,Yunping Qiu,Xia Zou,Tianlu Chen,Guoxiang Xie,Yu Cheng,Tao-Tao Dong,Linjing Zhao,Bo Feng,Xiaofang Hu,Lisa X. Xu,Aihua Zhao,Menghui Zhang,Guoxiang Cai,Sanjun Cai,Zhanxiang Zhou,Minhua Zheng,Yan Zhang,Wei Jia +18 more
TL;DR: A follow-up replication study aiming to identify a distinct serum metabolic signature of CRC with diagnostic potential demonstrated that a panel of serum metabolite markers is of great potential as a noninvasive diagnostic method for the detection of CRC.
Journal ArticleDOI
Metabolic Fate of Tea Polyphenols in Humans
Guoxiang Xie,Aihua Zhao,Linjing Zhao,Tianlu Chen,Huiyuan Chen,Xin Qi,Xiaojiao Zheng,Yan Ni,Yu Cheng,Ke Lan,Chun Yao,Mingfeng Qiu,Wei Jia +12 more
TL;DR: This study demonstrates that the metabonomic strategy will enable us to integrate the overwhelming amount of metabolic end points as a systems' response to the absorption, metabolism, and disposition of a multicomponent botanical intervention system, leading to a direct elucidation of their mechanisms of action.
Journal ArticleDOI
An ultrasonication-assisted extraction and derivatization protocol for GC/TOFMS-based metabolite profiling
TL;DR: An ultrasonication-assisted protocol is reported which reduces the derivatization time from hours to about 30 min and significantly enhances the deriv atization efficiency prior to a GC/TOFMS analysis.
Journal ArticleDOI
A simultaneously quantitative profiling method for 40 endogenous amino acids and derivatives in cell lines using hydrophilic interaction liquid chromatography coupled with tandem mass spectrometry
Bangjie Zhu,Li Li,Hai Wei,Wenbin Zhou,Wentao Zhou,Fugang Li,Peiyuan Lin,Jiaqiang Sheng,Qingjiang Wang,Chao Yan,Chao Yan,Yu Cheng,Yu Cheng +12 more
TL;DR: This quantified analytical method meets the requirement of quantification in specific expanded metabolomics studies with good sensitivity and was successfully applied to the analysis of amino acids and their derivatives in breast cancer cell samples.