H
Hye Sun Kim
Researcher at New Generation University College
Publications - 83
Citations - 3011
Hye Sun Kim is an academic researcher from New Generation University College. The author has contributed to research in topics: Oxidative stress & Amyloid precursor protein. The author has an hindex of 28, co-authored 78 publications receiving 2536 citations. Previous affiliations of Hye Sun Kim include UPRRP College of Natural Sciences & Korea Institute of Science and Technology.
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Silver nanoparticles induce oxidative cell damage in human liver cells through inhibition of reduced glutathione and induction of mitochondria-involved apoptosis
Mei Jing Piao,Kyoung Ah Kang,In Kyung Lee,Hye Sun Kim,Suhkmann Kim,Jeong Yun Choi,Jinhee Choi,Jin Won Hyun +7 more
TL;DR: In this paper, the authors investigated the possible molecular mechanisms underlying the cytotoxic effects of AgNPs and found that AgNs induced reactive oxygen species (ROS) generation and suppression of reduced glutathione (GSH) in human Chang liver cells.
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Neuroligin-1 controls synaptic abundance of NMDA-type glutamate receptors through extracellular coupling
Elaine C. Budreck,Oh Bin Kwon,Jung Hoon Jung,Stéphane J. Baudouin,Albert Thommen,Hye Sun Kim,Yugo Fukazawa,Harumi Harada,Katsuhiko Tabuchi,Katsuhiko Tabuchi,Ryuichi Shigemoto,Peter Scheiffele,Joung Hun Kim +12 more
TL;DR: Evidence is provided that NL1 regulates the abundance of NMDARs at postsynaptic sites and uncovers NL1 isoform-specific cis-interactions with ionotropic glutamate receptors as a key mechanism for controlling synaptic properties.
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The Preventive and Therapeutic Effects of Intravenous Human Adipose-Derived Stem Cells in Alzheimer’s Disease Mice
Saeromi Kim,Keun-A Chang,Keun-A Chang,Jeong A. Kim,Hyeong Geun Park,Jeong Chan Ra,Hye Sun Kim,Yoo-Hun Suh +7 more
TL;DR: It is reported that intravenously or intracerebrally transplanted hASCs significantly rescues memory deficit and neuropathology, in the brains of Tg mice by up-regulating IL-10 and VEGF and be a possible use for the prevention and treatment of AD.
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Amyloid β peptide induces cytochrome c release from isolated mitochondria
Hye Sun Kim,Jun Ho Lee,Jean Pyo Lee,Eun-Mee Kim,Keun-A Chang,Cheol Hyoung Park,Sung Jin Jeong,M. C. Wittendorp,Ji-Heui Seo,Se Hoon Choi,Yoo-Hun Suh +10 more
TL;DR: The results suggest that the A&bgr;accumulated intracellularly by APP processing might exert neurotoxicity by interacting with mitochondria and inducing mitochondrial swelling and release of Cyt c, which activates caspase-3 and finally can lead to apoptosis in neuronal cells and to neurodegeneration in AD.
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Biphasic Electrical Currents Stimulation Promotes both Proliferation and Differentiation of Fetal Neural Stem Cells
Keun-A Chang,Jin Won Kim,Jeong A. Kim,Sung-Eun Lee,Saeromi Kim,Won Hyuk Suh,Hye Sun Kim,Sunghoon Kwon,Sung June Kim,Yoo-Hun Suh +9 more
TL;DR: It is found that biphasic electrical currents (BECs) significantly increased the proliferation of fetal neural stem cells (NSCs) and promoted the differentiation of fetal NSCs into neuronal cells, as assessed using immunocytochemistry.