K
Kyoung Ah Kang
Researcher at Jeju National University
Publications - 133
Citations - 5336
Kyoung Ah Kang is an academic researcher from Jeju National University. The author has contributed to research in topics: Oxidative stress & Reactive oxygen species. The author has an hindex of 38, co-authored 124 publications receiving 4393 citations. Previous affiliations of Kyoung Ah Kang include New Generation University College.
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Journal ArticleDOI
Silver nanoparticles induce oxidative cell damage in human liver cells through inhibition of reduced glutathione and induction of mitochondria-involved apoptosis
Mei Jing Piao,Kyoung Ah Kang,In Kyung Lee,Hye Sun Kim,Suhkmann Kim,Jeong Yun Choi,Jinhee Choi,Jin Won Hyun +7 more
TL;DR: In this paper, the authors investigated the possible molecular mechanisms underlying the cytotoxic effects of AgNPs and found that AgNs induced reactive oxygen species (ROS) generation and suppression of reduced glutathione (GSH) in human Chang liver cells.
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Particulate matter 2.5 damages skin cells by inducing oxidative stress, subcellular organelle dysfunction, and apoptosis.
Mei Jing Piao,Mee Jung Ahn,Kyoung Ah Kang,Yea Seong Ryu,Yu Jae Hyun,Kristina Shilnikova,Ao Xuan Zhen,Jin Woo Jeong,Yung Hyun Choi,Hee Kyoung Kang,Young Sang Koh,Jin Won Hyun +11 more
TL;DR: The results indicate that PM2.5 induced oxidative stress by generating reactive oxygen species both in vitro and in vivo, which led to DNA damage, lipid peroxidation, and protein carbonylation, and caused apoptosis in HaCaT cells and mouse skin tissue.
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Eckol isolated from Ecklonia cava attenuates oxidative stress induced cell damage in lung fibroblast cells.
Kyoung Ah Kang,Kyoung Hwa Lee,Sungwook Chae,Rui Zhang,Myung Sun Jung,Young-Ki Lee,So Young Kim,Hee Sun Kim,Hong Gu Joo,Jae Woo Park,Young Min Ham,Nam Ho Lee,Jin Won Hyun +12 more
TL;DR: The results suggest that eckol protects V79‐4 cells against oxidative damage by enhancing the cellular antioxidant activity and modulating cellular signal pathway.
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Cytoprotective effect of phloroglucinol on oxidative stress induced cell damage via catalase activation.
Kyoung Ah Kang,Kyoung Hwa Lee,Sungwook Chae,Rui Zhang,Myung Sun Jung,Young Min Ham,Jong Seok Baik,Nam Ho Lee,Jin Won Hyun +8 more
TL;DR: The results suggest that phloroglucinol protects V79‐4 cells against oxidative damage by enhancing the cellular catalase activity and modulating ERK signal pathway.
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Up-regulation of Nrf2-mediated heme oxygenase-1 expression by eckol, a phlorotannin compound, through activation of Erk and PI3K/Akt.
Ki Cheon Kim,Kyoung Ah Kang,Rui Zhang,Mei Jing Piao,Gi-Young Kim,Mi Young Kang,Su Jae Lee,Nam Ho Lee,Young-Joon Surh,Jin Won Hyun +9 more
TL;DR: It is demonstrated that eckol attenuates oxidative stress by activating Nrf2-mediated HO-1 induction via Erk and PI3K/Akt signaling, and treatments with U0126 and LY294002 inhibited the eickol-induced cytoprotective effect against oxidative cell damage.