J
Joung Hun Kim
Researcher at Pohang University of Science and Technology
Publications - 57
Citations - 3356
Joung Hun Kim is an academic researcher from Pohang University of Science and Technology. The author has contributed to research in topics: Synaptic plasticity & Long-term potentiation. The author has an hindex of 25, co-authored 46 publications receiving 2971 citations. Previous affiliations of Joung Hun Kim include Inha University & Howard Hughes Medical Institute.
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Journal ArticleDOI
Integration of Long-Term-Memory-Related Synaptic Plasticity Involves Bidirectional Regulation of Gene Expression and Chromatin Structure
Zhonghui Guan,Maurizio Giustetto,Maurizio Giustetto,Stavros Lomvardas,Joung Hun Kim,Maria Concetta Miniaci,James H. Schwartz,Dimitris Thanos,Eric R. Kandel,Eric R. Kandel +9 more
TL;DR: Aplysia finds that when a sensory neuron simultaneously receives inputs from the facilitatory transmitter 5-HT at one set of synapses and the inhibitory transmitter FMRFamide at another, long-term facilitation is blocked and synapse-specific long- term depression dominates.
Journal ArticleDOI
A Neuronal Isoform of CPEB Regulates Local Protein Synthesis and Stabilizes Synapse-Specific Long-Term Facilitation in Aplysia
Kausik Si,Maurizio Giustetto,Amit Etkin,Ruby Hsu,Agnieszka M. Janisiewicz,Maria Conchetta Miniaci,Joung Hun Kim,Huixiang Zhu,Eric R. Kandel,Eric R. Kandel +9 more
TL;DR: It is suggested that Aplysia CPEB is one of the stabilizing components of the synaptic mark, which is needed not for the initiation but for the stable maintenance of long-term facilitation.
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Neuroligin-1 controls synaptic abundance of NMDA-type glutamate receptors through extracellular coupling
Elaine C. Budreck,Oh Bin Kwon,Jung Hoon Jung,Stéphane J. Baudouin,Albert Thommen,Hye Sun Kim,Yugo Fukazawa,Harumi Harada,Katsuhiko Tabuchi,Katsuhiko Tabuchi,Ryuichi Shigemoto,Peter Scheiffele,Joung Hun Kim +12 more
TL;DR: Evidence is provided that NL1 regulates the abundance of NMDARs at postsynaptic sites and uncovers NL1 isoform-specific cis-interactions with ionotropic glutamate receptors as a key mechanism for controlling synaptic properties.
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Exosomes neutralize synaptic-plasticity-disrupting activity of Aβ assemblies in vivo
Kyongman An,Igor Klyubin,Youngkyu Kim,Jung Hoon Jung,Alexandra J. Mably,Alexandra J. Mably,Seán O'Dowd,Seán O'Dowd,Timothy Lynch,Daniel Kanmert,Cynthia A. Lemere,Gina M. Finan,Joon Won Park,Tae-Wan Kim,Dominic M. Walsh,Michael J. Rowan,Joung Hun Kim +16 more
TL;DR: In vivo evidence that exosomes derived from N2a cells or human cerebrospinal fluid can abrogate the synaptic-plasticity-disrupting activity of both synthetic and AD brain-derived Aβ is provided.
Journal ArticleDOI
Neuroligin-1 is required for normal expression of LTP and associative fear memory in the amygdala of adult animals
Juhyun Kim,Sang-Yong Jung,Yeon Kyung Lee,Sang Ki Park,June-Seek Choi,C. Justin Lee,Hye-Sun Kim,Yun-Beom Choi,Peter Scheiffele,Craig H. Bailey,Eric R. Kandel,Joung Hun Kim +11 more
TL;DR: Results indicate that persistent expression of neuroligin-1 is required for the maintenance of NMDAR-mediated synaptic transmission, which enables normal development of synaptic plasticity and long-term memory in the amygdala of adult animals.