H
Hyoung F. Kim
Researcher at Seoul National University
Publications - 44
Citations - 3156
Hyoung F. Kim is an academic researcher from Seoul National University. The author has contributed to research in topics: Aplysia & Basal ganglia. The author has an hindex of 24, co-authored 40 publications receiving 2838 citations. Previous affiliations of Hyoung F. Kim include Sungkyunkwan University & National Institutes of Health.
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Journal ArticleDOI
Regulation of B cell differentiation and plasma cell generation by IL-21, a novel inducer of Blimp-1 and Bcl-6
Katsutoshi Ozaki,Katsutoshi Ozaki,Rosanne Spolski,Rachel Ettinger,Hyoung F. Kim,Gang Wang,Chen Feng Qi,Patrick Hwu,Daniel J. Shaffer,Shreeram Akilesh,Derry C. Roopenian,Herbert C. Morse,Peter E. Lipsky,Warren J. Leonard +13 more
TL;DR: It is demonstrated that although IL-21 induces death of resting B cells, it promotes differentiation of B cells into postswitch and plasma cells, explaining howIL-21 can be proapoptotic for B cells in vitro yet critical for Ag-specific Ig production in vivo.
Predictive Reward Signal of Dopamine Neurons
Kazuko Hayashi,Kazuko Nakao,Kae Nakamura,Athanasia M. Mowinckel,Mads Lund Pedersen,Espen Moen Eilertsen,Guido Biele,Hyoung F. Kim,Okihide Hikosaka +8 more
Journal ArticleDOI
Synaptic protein degradation underlies destabilization of retrieved fear memory.
Sue-Hyun Lee,Jun-Hyeok Choi,Nuribalhae Lee,Hye-Ryeon Lee,Jae-Ick Kim,Nam-Kyung Yu,Sun-Lim Choi,Seung-Hee Lee,Hyoung F. Kim,Bong-Kiun Kaang +9 more
TL;DR: It is found that postsynaptic proteins were degraded in the hippocampus by polyubiquitination after retrieval of contextual fear memory, and the infusion of proteasome inhibitor into the CA1 region immediately after retrieval prevented anisomycin-induced memory impairment, as well as the extinction of fear memory.
Journal ArticleDOI
Basal ganglia circuits for reward value-guided behavior
TL;DR: The basal ganglia are equipped with inhibitory and disinhibitory mechanisms that enable a subject to choose valuable objects and actions and contain an equivalent parallel mechanism for action values, which create a highly adaptable system for decision making.
Journal ArticleDOI
Distinct basal ganglia circuits controlling behaviors guided by flexible and stable values.
Hyoung F. Kim,Okihide Hikosaka +1 more
TL;DR: It is found that distinct circuits of the primate caudate nucleus control behavior selectively in the flexible and stable value conditions and inactivation of each caUDate subregion disrupted the high-low value discrimination selectively in a flexible or stable context.