H
Hyun Jai Cho
Researcher at Seoul National University Hospital
Publications - 187
Citations - 4600
Hyun Jai Cho is an academic researcher from Seoul National University Hospital. The author has contributed to research in topics: Heart failure & Medicine. The author has an hindex of 33, co-authored 127 publications receiving 3750 citations. Previous affiliations of Hyun Jai Cho include Tufts University & Seoul National University.
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Journal ArticleDOI
Synergistic neovascularization by mixed transplantation of early endothelial progenitor cells and late outgrowth endothelial cells: the role of angiogenic cytokines and matrix metalloproteinases.
Chang Hwan Yoon,Jin Hur,Kyung Woo Park,Ji Hyun Kim,Choon Soo Lee,Il-Young Oh,Tae Youn Kim,Hyun Jai Cho,Hyun Jae Kang,In Ho Chae,Han-Kwang Yang,Byung Hee Oh,Young Bae Park,Hyo-Soo Kim +13 more
TL;DR: Distinct origins of the different types of EPCs exist that have different functions in neovascularization, and mixed transplantation of these cells results in synergistic neov vascularization through cytokines and MMPs.
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Malignant Tumor Formation After Transplantation of Short-Term Cultured Bone Marrow Mesenchymal Stem Cells in Experimental Myocardial Infarction and Diabetic Neuropathy
Jin Ok Jeong,Ji Woong Han,Jin Man Kim,Hyun Jai Cho,Hyun Jai Cho,Changwon Park,Changwon Park,Namho Lee,Namho Lee,Dong-Wook Kim,Young Sup Yoon +10 more
TL;DR: Genetically unmodified MSCs can undergo chromosomal abnormalities even at early passages and form malignant tumors when transplanted in vivo, suggesting that careful monitoring of chromosomal status is warranted when in vitro expanded M SCs are used for cell therapy such as for MI.
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Induction of pluripotent stem cells from adult somatic cells by protein-based reprogramming without genetic manipulation
Hyun Jai Cho,Choon Soo Lee,Yoo Wook Kwon,Jae Seung Paek,Sun Hee Lee,Jin Hur,Eun Ju Lee,Tae-Young Roh,In Sun Chu,Sun Hee Leem,Youngsoo Kim,Hyun Jae Kang,Young Bae Park,Hyo-Soo Kim +13 more
TL;DR: It is reported that that a single transfer of embryonic stem (ES) cell-derived proteins into primarily cultured adult mouse fibroblasts, rather than repeated transfer or prolonged exposure to materials, can achieve full reprogramming up to the pluripotent state without the forced expression of ectopic transgenes.
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Osteopontin: A multifunctional protein at the crossroads of inflammation, atherosclerosis, and vascular calcification
TL;DR: The role of OPN in vascular calcification (VC), which is closely related to chronic and active inflammation, is that of a negative regulator because it is an inhibitor of calcification and an active inducer of decalcification.
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A multicentre cohort study of acute heart failure syndromes in Korea: Rationale, design, and interim observations of the Korean Acute Heart Failure (KorAHF) registry
Sang Eun Lee,Hyun Jai Cho,Hae Young Lee,Han Mo Yang,Jin-Oh Choi,Eun Seok Jeon,Min-Seok Kim,Jae Joong Kim,Kyung-Kuk Hwang,Shung Chull Chae,Suk Min Seo,Sang Hong Baek,Seok Min Kang,Il Young Oh,Dong-Ju Choi,Byung Su Yoo,Youngkeun Ahn,Hyun Young Park,Myeong Chan Cho,Byung Hee Oh +19 more
TL;DR: The Korean Acute Heart Failure registry (KorAHF) aims to evaluate the clinical characteristics, management, hospital course, and long‐term outcomes of patients hospitalized for acute heart failure syndrome in Korea.