Ian O. Ellis

TL;DR: A two phase testing algorithm based on first line immunocytochemistry evaluation and second line fluorescence in situ hybridization assessment of borderline cases is recommended in this article, where emphasis is placed on the standardisation of methodology and assessment and strategies to achieve high quality performance.

TL;DR: This study did not show any overall gain from the addition of docetaxel to standard anthracycline chemotherapy, and exploration of predictive biomarker-defined subgroups might have the potential to better target the use of taxane-based therapy.

TL;DR: A review of the literature indicated variable underestimation rates for breast core-needle biopsy (CNB) based on generally small series was 27.7% (95% confidence interval [95% CI], 24.5-30.9% as mentioned in this paper.

TL;DR: In conclusion, VI in breast cancer is predominantly of lymph vessels and is a powerful independent prognostic factor, which is associated with risk of recurrence and death from the disease.

TL;DR: Even in these patients with tumours of excellent prognosis, LR after conservative surgery without adjuvant therapy was still very high and was reduced to a similar extent by either radiotherapy or tamoxifen but to a greater extent by the receipt of both treatments.